Search Results for: AP2M1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
FXR2 FMR1 autosomal homolog 2
GAK cyclin G associated kinase
  • Golgi Associated Vesicle Biogenesis
  • Clathrin-mediated endocytosis
  • Fostamatinib
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Neurexins and neuroligins
  • Synaptic adhesion-like molecules
  • MECP2 regulates neuronal receptors and channels
  • Assembly and cell surface presentation of NMDA receptors
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
  • Glutamic acid
  • Glycine
  • Tramadol
  • Enflurane
  • Atomoxetine
  • Pentobarbital
  • Methadone
  • Secobarbital
  • Meperidine
  • Dextropropoxyphene
  • Acamprosate
  • Donepezil
  • Guaifenesin
  • Felbamate
  • Memantine
  • Halothane
  • Phenobarbital
  • Aripiprazole
  • Tenocyclidine
  • Prasterone
  • Milnacipran
  • Acetylcysteine
  • Ketobemidone
  • Gavestinel
  • Magnesium acetate tetrahydrate
  • Magnesium carbonate
  • Esketamine
  • Fluciclovine (18F)
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Ras activation upon Ca2+ influx through NMDA receptor
  • RAF/MAP kinase cascade
  • Neurexins and neuroligins
  • Synaptic adhesion-like molecules
  • MECP2 regulates neuronal receptors and channels
  • Activated NTRK2 signals through FYN
  • Assembly and cell surface presentation of NMDA receptors
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
  • Glutamic acid
  • Tramadol
  • Enflurane
  • Atomoxetine
  • Pentobarbital
  • Methadone
  • Secobarbital
  • Meperidine
  • Haloperidol
  • Dextropropoxyphene
  • Acamprosate
  • Donepezil
  • Guaifenesin
  • Felbamate
  • Memantine
  • Phenobarbital
  • Aripiprazole
  • Tenocyclidine
  • Prasterone
  • Taurine
  • Milnacipran
  • EVT-101
  • Lumateperone
  • Acetylcysteine
  • Ketobemidone
  • Gavestinel
  • Ifenprodil
  • Magnesium acetate tetrahydrate
  • Magnesium carbonate
  • Esketamine
  • Esketamine
  • Fluciclovine (18F)
H2BC10 H2B clustered histone 10
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • E3 ubiquitin ligases ubiquitinate target proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
  • Copper
H2BC13 H2B clustered histone 13
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • E3 ubiquitin ligases ubiquitinate target proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
H2BC21 H2B clustered histone 21
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
H2BC4 H2B clustered histone 4
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • E3 ubiquitin ligases ubiquitinate target proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
  • Copper
H2BC6 H2B clustered histone 6
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • E3 ubiquitin ligases ubiquitinate target proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
  • Copper
H2BC7 H2B clustered histone 7
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • E3 ubiquitin ligases ubiquitinate target proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
  • Copper
H2BC8 H2B clustered histone 8
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Pre-NOTCH Transcription and Translation
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • PRC2 methylates histones and DNA
  • Condensation of Prophase Chromosomes
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • HDACs deacetylate histones
  • HATs acetylate histones
  • HATs acetylate histones
  • SIRT1 negatively regulates rRNA expression
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • DNA methylation
  • Transcriptional regulation by small RNAs
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Ub-specific processing proteases
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Assembly of the ORC complex at the origin of replication
  • G2/M DNA damage checkpoint
  • RNA Polymerase I Promoter Opening
  • RNA Polymerase I Promoter Escape
  • E3 ubiquitin ligases ubiquitinate target proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Estrogen-dependent gene expression
  • Meiotic recombination
  • HCMV Early Events
  • HCMV Late Events
  • Transcriptional regulation of granulopoiesis
  • Inhibition of DNA recombination at telomere
  • Defective pyroptosis
  • Negative Regulation of CDH1 Gene Transcription
  • Amyloid fiber formation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
  • Replacement of protamines by nucleosomes in the male pronucleus
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by KRAB-ZFP proteins
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Regulation of PD-L1(CD274) transcription
  • Copper
HEXIM2 HEXIM P-TEFb complex subunit 2
HOOK2 hook microtubule tethering protein 2
HTR6 5-hydroxytryptamine receptor 6
  • Serotonin receptors
  • G alpha (s) signalling events
  • Ziprasidone
  • Amitriptyline
  • Olanzapine
  • Clozapine
  • Loxapine
  • Imipramine
  • Chlorpromazine
  • Haloperidol
  • Amoxapine
  • Paroxetine
  • Cyclobenzaprine
  • Ergoloid mesylate
  • Doxepin
  • Quetiapine
  • Aripiprazole
  • Chlorprothixene
  • Dimethyltryptamine
  • Lysergic acid diethylamide
  • Iloperidone
  • SGS518
  • PRX-07034
  • SUVN-502
  • Sertindole
  • Mianserin
  • Asenapine
  • Zotepine
  • Setiptiline
  • Dihydroergocornine
  • Gilteritinib
  • Tiapride
  • Dihydroergocristine
  • Aripiprazole lauroxil
IKZF1 IKAROS family zinc finger 1
IRS2 insulin receptor substrate 2
  • PI3K Cascade
  • IRS-mediated signalling
  • SOS-mediated signalling
  • SOS-mediated signalling
  • PIP3 activates AKT signaling
  • Interleukin-7 signaling
  • PI3K/AKT activation
  • PI3K/AKT activation
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • IRS-related events triggered by IGF1R
  • Signaling by Leptin
  • RAF/MAP kinase cascade
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • IRS activation
  • Signal attenuation
  • RET signaling
  • Signaling by Erythropoietin
  • Signaling by Erythropoietin
  • Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
  • Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
  • Erythropoietin activates Phospholipase C gamma (PLCG)
  • Erythropoietin activates STAT5
  • Erythropoietin activates RAS
  • Erythropoietin activates RAS
  • Growth hormone receptor signaling
KCNJ11 potassium inwardly rectifying channel subfamily J member 11
  • ATP sensitive Potassium channels
  • ABC-family proteins mediated transport
  • Regulation of insulin secretion
  • Ion homeostasis
  • Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome
  • Defective ABCC8 can cause hypo- and hyper-glycemias
  • Glimepiride
  • Ibutilide
  • Verapamil
  • Tolazamide
  • Ritodrine
  • Levosimendan
  • Glyburide
  • Glyburide
  • Diazoxide
  • Thiamylal
  • Yohimbine
  • Butamben
  • Isavuconazole
  • Permanent neonatal diabetes mellitus (PNDM)
  • Transient neonatal diabetes mellitus (TNDM)
  • Type II diabetes mellitus
KNOP1 lysine rich nucleolar protein 1
LAMP1 lysosomal associated membrane protein 1
  • Neutrophil degranulation
LTB4R2 leukotriene B4 receptor 2
  • Leukotriene receptors
  • G alpha (q) signalling events
  • Amelubant
  • Leukotriene B4

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