FXR1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ANKS3	ankyrin repeat and sterile alpha motif domain containing 3
AP1M1	adaptor related protein complex 1 subunit mu 1	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
APC2	APC regulator of Wnt signaling pathway 2			Colorectal cancer
ARHGAP22	Rho GTPase activating protein 22	RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
ARHGEF7	Rho guanine nucleotide exchange factor 7	EGFR downregulation NRAGE signals death through JNK Ephrin signaling G alpha (12/13) signalling events RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RHOV GTPase cycle
ATN1	atrophin 1	Regulation of PTEN gene transcription		Dentatorubropallidoluysian atrophy (DRPLA)
AXIN1	axin 1	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade TCF dependent signaling in response to WNT Degradation of AXIN Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane Signaling by GSK3beta mutants CTNNB1 S33 mutants aren't phosphorylated CTNNB1 S37 mutants aren't phosphorylated CTNNB1 S45 mutants aren't phosphorylated CTNNB1 T41 mutants aren't phosphorylated APC truncation mutants have impaired AXIN binding AXIN missense mutants destabilize the destruction complex Truncations of AMER1 destabilize the destruction complex Ub-specific processing proteases RUNX1 regulates estrogen receptor mediated transcription RUNX1 regulates transcription of genes involved in WNT signaling Estrogen-dependent gene expression	1,4-Dithiothreitol	Caudal duplication anomaly Hepatocellular carcinoma
AXIN2	axin 2	TCF dependent signaling in response to WNT Binding of TCF/LEF:CTNNB1 to target gene promoters Degradation of AXIN Ub-specific processing proteases		Oligodontia-colorectal cancer syndrome Tooth agenesis; Hypodontia
BCKDK	branched chain keto acid dehydrogenase kinase	Branched-chain amino acid catabolism Branched-chain ketoacid dehydrogenase kinase deficiency	Adenosine 5'-[gamma-thio]triphosphate
BEND5	BEN domain containing 5
BHLHE40	basic helix-loop-helix family member e40	BMAL1:CLOCK,NPAS2 activates circadian expression Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
BICD1	BICD cargo adaptor 1	COPI-independent Golgi-to-ER retrograde traffic
BLK	BLK proto-oncogene, Src family tyrosine kinase	RUNX1 regulates transcription of genes involved in BCR signaling Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Fostamatinib Zanubrutinib	Maturity onset diabetes of the young (MODY)
BLTP3B	bridge-like lipid transfer protein family member 3B	RND2 GTPase cycle
BTBD2	BTB domain containing 2
BTBD6	BTB domain containing 6	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
BYSL	bystin like	Major pathway of rRNA processing in the nucleolus and cytosol
C1orf35	chromosome 1 open reading frame 35	Neutrophil degranulation
CA10	carbonic anhydrase 10		Zonisamide
CACTIN-AS1	CACTIN antisense RNA 1

Search Results for: FXR1