Search Results for: CLU

68 interactions involving CLU - clusterin found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A
  • G0 and Early G1
  • N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide
  • Fostamatinib
ELN elastin
  • Degradation of the extracellular matrix
  • Elastic fibre formation
  • Molecules associated with elastic fibres
  • Molecules associated with elastic fibres
  • Rofecoxib
  • Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
  • Congenital supravalvar aortic stenosis
EPPIN epididymal peptidase inhibitor
  • Antimicrobial peptides
ETS2 ETS proto-oncogene 2, transcription factor
  • Oncogene Induced Senescence
FOS Fos proto-oncogene, AP-1 transcription factor subunit
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • FCERI mediated MAPK activation
  • Activation of the AP-1 family of transcription factors
  • Interleukin-4 and Interleukin-13 signaling
  • TP53 Regulates Transcription of DNA Repair Genes
  • Estrogen-dependent gene expression
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • NPAS4 regulates expression of target genes
  • Regulation of PD-L1(CD274) transcription
  • Pseudoephedrine
  • Nandrolone decanoate
  • Nadroparin
GRB2 growth factor receptor bound protein 2
  • Interleukin-15 signaling
  • Interleukin-15 signaling
  • Signaling by CSF3 (G-CSF)
  • Signaling by CSF3 (G-CSF)
  • STAT5 activation downstream of FLT3 ITD mutants
  • Signaling by FLT3 ITD and TKD mutants
  • Signaling by FLT3 ITD and TKD mutants
  • Signaling by ALK fusions and activated point mutants
  • Signaling by LTK
  • Pegademase
  • 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
HSPA13 heat shock protein family A (Hsp70) member 13
  • Regulation of HSF1-mediated heat shock response
  • Copper
HSPD1 heat shock protein family D (Hsp60) member 1
  • Mitochondrial protein import
  • Mitochondrial protein import
  • TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
  • Mitochondrial protein degradation
  • Mitochondrial unfolded protein response (UPRmt)
  • Copper
  • Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
  • Hereditary spastic paraplegia (SPG)
HUNK hormonally up-regulated Neu-associated kinase
IL24 interleukin 24
  • Interleukin-20 family signaling
KATNA1 katanin catalytic subunit A1
KEAP1 kelch like ECH associated protein 1
  • Ub-specific processing proteases
  • Neddylation
  • Potential therapeutics for SARS
  • KEAP1-NFE2L2 pathway
  • Nuclear events mediated by NFE2L2
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Dimethyl fumarate
KLF11 KLF transcription factor 11
  • Maturity onset diabetes of the young (MODY)
KNSTRN kinetochore localized astrin (SPAG5) binding protein
LCOR ligand dependent nuclear receptor corepressor
LEP leptin
  • Signaling by Leptin
  • Transcriptional regulation of white adipocyte differentiation
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Synthesis, secretion, and deacylation of Ghrelin
LEPR leptin receptor
  • Leptin
  • Metreleptin
LIG4 DNA ligase 4
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
LRP1 LDL receptor related protein 1
  • Scavenging of heme from plasma
  • Retinoid metabolism and transport
  • Antihemophilic factor, human recombinant
  • Tenecteplase
  • Coagulation Factor IX (Recombinant)
  • Lanoteplase
  • Von Willebrand factor human
  • Coagulation Factor IX Human
  • Lonoctocog alfa
  • Moroctocog alfa
LRP2 LDL receptor related protein 2
  • Vitamin D (calciferol) metabolism
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • Retinoid metabolism and transport
  • Transport of RCbl within the body
  • Urokinase
  • Insulin human
  • Donnai-Barrow syndrome; Faciooculoacousticorenal syndrome

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