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CD22
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CD22 molecule |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- CD22 mediated BCR regulation
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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- Epratuzumab
- Inotuzumab ozogamicin
- Moxetumomab pasudotox
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CD2BP2
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CD2 cytoplasmic tail binding protein 2 |
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CD3D
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CD3 delta subunit of T-cell receptor complex |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- Downstream TCR signaling
- Phosphorylation of CD3 and TCR zeta chains
- Translocation of ZAP-70 to Immunological synapse
- Generation of second messenger molecules
- Co-inhibition by PD-1
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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- Muromonab
- Blinatumomab
- Teclistamab
- Odronextamab
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- T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
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CDK11B
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cyclin dependent kinase 11B |
- Recruitment of mitotic centrosome proteins and complexes
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CEBPA
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CCAAT enhancer binding protein alpha |
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
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- Acute myeloid leukemia (AML)
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CLK2
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CDC like kinase 2 |
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CORO7
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coronin 7 |
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CSNK2B
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casein kinase 2 beta |
- Synthesis of PC
- WNT mediated activation of DVL
- Condensation of Prometaphase Chromosomes
- Signal transduction by L1
- Neutrophil degranulation
- Regulation of TP53 Activity through Phosphorylation
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- Receptor Mediated Mitophagy
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- Regulation of PTEN stability and activity
- KEAP1-NFE2L2 pathway
- Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
- Maturation of hRSV A proteins
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
- Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
- Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
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CTLA4
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cytotoxic T-lymphocyte associated protein 4 |
- Co-stimulation by CD28
- Co-inhibition by CTLA4
- RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
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- Abatacept
- Ipilimumab
- Tremelimumab
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- Graves' disease
- Allograft rejection
- Type I diabetes mellitus
- Hashimoto's thyroiditis
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CXorf51A
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chromosome X open reading frame 51A |
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CXorf51B
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chromosome X open reading frame 51B |
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DAB2
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DAB adaptor protein 2 |
- Gap junction degradation
- Formation of annular gap junctions
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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DCX
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doublecortin |
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- Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
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DPPA2
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developmental pluripotency associated 2 |
- Zygotic genome activation (ZGA)
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DVL2
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dishevelled segment polarity protein 2 |
- TCF dependent signaling in response to WNT
- WNT mediated activation of DVL
- Signaling by Hippo
- PCP/CE pathway
- PCP/CE pathway
- Asymmetric localization of PCP proteins
- Degradation of DVL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- WNT5A-dependent internalization of FZD4
- Negative regulation of TCF-dependent signaling by DVL-interacting proteins
- RHO GTPases Activate Formins
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- WNT5:FZD7-mediated leishmania damping
- WNT5:FZD7-mediated leishmania damping
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EAF1
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ELL associated factor 1 |
- Formation of RNA Pol II elongation complex
- RNA Polymerase II Pre-transcription Events
- RNA Polymerase II Transcription Elongation
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EHD2
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EH domain containing 2 |
- Factors involved in megakaryocyte development and platelet production
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EIF1AD
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eukaryotic translation initiation factor 1A domain containing |
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FAM90A1
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family with sequence similarity 90 member A1 |
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FURIN
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furin, paired basic amino acid cleaving enzyme |
- Signaling by NODAL
- Collagen degradation
- Collagen degradation
- Elastic fibre formation
- Activation of Matrix Metalloproteinases
- Removal of aminoterminal propeptides from gamma-carboxylated proteins
- NGF processing
- Synthesis and processing of ENV and VPU
- Signaling by PDGF
- Pre-NOTCH Processing in Golgi
- TGF-beta receptor signaling activates SMADs
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Uptake and function of anthrax toxins
- Formation of the cornified envelope
- Assembly of active LPL and LIPC lipase complexes
- CD163 mediating an anti-inflammatory response
- Potential therapeutics for SARS
- Attachment and Entry
- Induction of Cell-Cell Fusion
- Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
- Amyloid fiber formation
- Respiratory syncytial virus (RSV) attachment and entry
- Maturation of hRSV A proteins
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