Search Results for: TRAF1

249 interactions involving TRAF1 - TNF receptor associated factor 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
TNFRSF19 TNF receptor superfamily member 19
TNFRSF1A TNF receptor superfamily member 1A
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR1-mediated ceramide production
  • TNFs bind their physiological receptors
  • Interleukin-10 signaling
  • TNF signaling
  • 6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One
  • Tasonermin
  • Tumor necrosis factor receptor-associated periodic syndrome (TRAPS); Familial periodic fever
TNFRSF1B TNF receptor superfamily member 1B
  • TNFR2 non-canonical NF-kB pathway
  • TNFs bind their physiological receptors
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • Neutrophil degranulation
  • Tasonermin
  • Graft-versus-host disease
TNFRSF4 TNF receptor superfamily member 4
  • TNFs bind their physiological receptors
TNFRSF8 TNF receptor superfamily member 8
  • TNFs bind their physiological receptors
  • Iratumumab
  • XmAb 2513
  • Brentuximab vedotin
TNFRSF9 TNF receptor superfamily member 9
  • TNFs bind their physiological receptors
  • Urelumab
TNFSF9 TNF superfamily member 9
  • TNFs bind their physiological receptors
TRADD TNFRSF1A associated via death domain
  • Caspase activation via Death Receptors in the presence of ligand
  • Regulation by c-FLIP
  • RIPK1-mediated regulated necrosis
  • CASP8 activity is inhibited
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • Regulation of necroptotic cell death
  • Dimerization of procaspase-8
  • TNF signaling
  • Defective RIPK1-mediated regulated necrosis
TRAF2 TNF receptor associated factor 2
  • Caspase activation via Death Receptors in the presence of ligand
  • Regulation by c-FLIP
  • RIPK1-mediated regulated necrosis
  • CASP8 activity is inhibited
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • Dimerization of procaspase-8
  • TNF signaling
  • TRAF6 mediated IRF7 activation
  • TRAF6 mediated NF-kB activation
  • TRAF6 mediated NF-kB activation
  • Defective RIPK1-mediated regulated necrosis
  • Regulation of NF-kappa B signaling
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor associated factor 6
  • PIP3 activates AKT signaling
  • MyD88:MAL(TIRAP) cascade initiated on plasma membrane
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • Regulated proteolysis of p75NTR
  • Downstream TCR signaling
  • NRIF signals cell death from the nucleus
  • NRIF signals cell death from the nucleus
  • p75NTR recruits signalling complexes
  • NF-kB is activated and signals survival
  • FCERI mediated NF-kB activation
  • TAK1-dependent IKK and NF-kappa-B activation
  • activated TAK1 mediates p38 MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • CLEC7A (Dectin-1) signaling
  • Ub-specific processing proteases
  • Ovarian tumor domain proteases
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • TICAM1,TRAF6-dependent induction of TAK1 complex
  • Interleukin-1 signaling
  • TRAF6 mediated IRF7 activation
  • TRAF6 mediated NF-kB activation
  • TRAF6 mediated NF-kB activation
  • IRAK1 recruits IKK complex
  • IKK complex recruitment mediated by RIP1
  • IRAK2 mediated activation of TAK1 complex
  • TRAF6-mediated induction of TAK1 complex within TLR4 complex
  • Alpha-protein kinase 1 signaling pathway
  • SARS-CoV-1 activates/modulates innate immune responses
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
  • TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
  • IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
  • MyD88 dependent cascade initiated on endosome
  • IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
  • Regulation of NF-kappa B signaling
  • MyD88 cascade initiated on plasma membrane
TRAIP TRAF interacting protein
  • Antigen processing: Ubiquitination & Proteasome degradation
TRIM23 tripartite motif containing 23
TRIM37 tripartite motif containing 37
  • Antigen processing: Ubiquitination & Proteasome degradation
TRIM42 tripartite motif containing 42
TRPV6 transient receptor potential cation channel subfamily V member 6
  • TRP channels
TSHZ2 teashirt zinc finger homeobox 2
TSSC4 tumor suppressing subtransferable candidate 4
USP2 ubiquitin specific peptidase 2
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • Ub-specific processing proteases
  • Regulation of TP53 Degradation
USP7 ubiquitin specific peptidase 7
  • Ub-specific processing proteases
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Regulation of TP53 Degradation
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • Regulation of PTEN localization

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