ACP6 and GNG7

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		ACP6	GNG7
Name		acid phosphatase 6, lysophosphatidic	G protein subunit gamma 7
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Heterotrimeric G-protein Complex Plasma Membrane Membrane Synapse Extracellular Exosome
	Molecular Function	Acid Phosphatase Activity Hydrolase Activity Lysophosphatidic Acid Phosphatase Activity	Protein Binding G-protein Beta-subunit Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Lysobisphosphatidic Acid Metabolic Process	Behavioral Fear Response Signal Transduction Receptor Guanylyl Cyclase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Locomotory Behavior Regulation Of G Protein-coupled Receptor Signaling Pathway
Pathways		Synthesis of PA	Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
GWAS		Blood protein levels ( 30072576 ) Methotrexate-induced interstitial lung disease in rheumatoid arthritis ( 28500057 )	Chronotype ( 30696823 ) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444 ) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223 ) HDL cholesterol levels ( 32203549 ) Heel bone mineral density ( 30598549 ) Neutrophil count ( 32888494 ) Thyroid stimulating hormone levels ( 32769997 )
Interacting Genes		3 interacting genes: FAM9B GNG7 SLC35F6	8 interacting genes: ACP6 GNB1 GNB2 GNB3 GNB4 GNB5 GORASP2 MPP3
Entrez ID		51205	2788
HPRD ID		16472	10376
Ensembl ID		ENSG00000162836	ENSG00000176533
Uniprot IDs		Q9NPH0	O60262
PDB IDs		4JOB 4JOC 4JOD	Not available
GO Terms Enriched among Interactors		None	Signaling Receptor Complex Adaptor Activity Heterotrimeric G-protein Complex GTPase Binding GTPase Activity G Protein-coupled Receptor Signaling Pathway G Protein-coupled Dopamine Receptor Signaling Pathway Protein-containing Complex Binding Lysosomal Membrane Synapse GTPase Activator Complex G-protein Gamma-subunit Binding Dark Adaptation Lysobisphosphatidic Acid Metabolic Process Light Adaption Regulation Of Locomotion Involved In Locomotory Behavior Acid Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Cell Tip