ACP6 and GNG7

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACP6	GNG7
Gene Name		acid phosphatase 6, lysophosphatidic	guanine nucleotide binding protein (G protein), gamma 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion	Heterotrimeric G-protein Complex Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Acid Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity	Signal Transducer Activity
	Biological Process	Phospholipid Metabolic Process Dephosphorylation Lysobisphosphatidic Acid Metabolic Process	Behavioral Fear Response Energy Reserve Metabolic Process Receptor Guanylyl Cyclase Signaling Pathway G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Locomotory Behavior Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Small Molecule Metabolic Process Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus
Pathways			Signaling by GPCR Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 1 Integration of energy metabolism G alpha (s) signalling events Activation of GABAB receptors Glucagon-type ligand receptors G beta:gamma signalling through PLC beta Signaling by Wnt Metabolic disorders of biological oxidation enzymes G protein gated Potassium channels Gastrin-CREB signalling pathway via PKC and MAPK Thromboxane signalling through TP receptor G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell ADP signalling through P2Y purinoceptor 12 Glucagon signaling in metabolic regulation Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Inwardly rectifying K+ channels G-protein beta:gamma signalling Opioid Signalling Activation of Kainate Receptors upon glutamate binding Aquaporin-mediated transport Adrenaline,noradrenaline inhibits insulin secretion G alpha (q) signalling events GPCR downstream signaling Platelet homeostasis Platelet activation, signaling and aggregation Transmission across Chemical Synapses G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signal amplification Potassium Channels G beta:gamma signalling through PI3Kgamma G alpha (12/13) signalling events Class B/2 (Secretin family receptors) Prostacyclin signalling through prostacyclin receptor GABA B receptor activation GABA receptor activation Activation of G protein gated Potassium channels Vasopressin regulates renal water homeostasis via Aquaporins Regulation of insulin secretion GPCR ligand binding beta-catenin independent WNT signaling Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Ca2+ pathway G-protein activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: FAM9B GNG7 SLC35F6	7 interactors: ACP6 GNB1 GNB2 GNB3 GNB4 GNB5 MPP3
Entrez ID		51205	2788
HPRD ID		16472	10376
Ensembl ID			ENSG00000176533
Uniprot IDs		Q9NPH0	O60262
PDB IDs		4JOB 4JOC 4JOD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway Negative Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Behavioral Fear Response Cellular Response To Glucagon Stimulus Fear Response Response To Glucagon Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Regulation Of CAMP Biosynthetic Process Multicellular Organismal Response To Stress Regulation Of Mitochondrion Organization Regulation Of CAMP Metabolic Process Negative Regulation Of Intracellular Transport Energy Reserve Metabolic Process	Cellular Response To Glucagon Stimulus Response To Glucagon Energy Reserve Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Generation Of Precursor Metabolites And Energy Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Cellular Response To Hormone Stimulus Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Response To Organonitrogen Compound Response To Hormone Small Molecule Metabolic Process G-protein Coupled Receptor Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Lysobisphosphatidic Acid Metabolic Process Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Oxidation-reduction Process Synaptic Transmission Signal Transduction Cellular Response To Radiation Signaling Cellular Response To Organic Substance Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Cell Communication Negative Regulation Of Voltage-gated Calcium Channel Activity Cell-cell Signaling Cardiac Muscle Cell Apoptotic Process Muscle Cell Apoptotic Process Cellular Response To Stimulus Response To Organic Substance Cellular Response To Prostaglandin E Stimulus Response To Light Stimulus G-protein Coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Response To Prostaglandin E Cellular Response To Prostaglandin Stimulus Negative Regulation Of Cation Channel Activity Regulation Of Voltage-gated Calcium Channel Activity Response To Radiation Cell Surface Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus
Tagcloud ?			adjust adora2a avp cart cecal clp intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd prkch puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
Tagcloud (Difference) ?			adjust adora2a avp cart cecal clp intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd prkch puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
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