APBA3

Name	amyloid beta precursor protein binding family A member 3
Structure
Novel Interactors	2 novel interactors: BDNF GPX4
Interactors	8 interactors: APP ARF3 ARF4 AZI2 BCR EGFR TANK TBKBP1
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Dendritic Spine Perinuclear Region Of Cytoplasm
	Molecular Function	Amyloid-beta Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding
	Biological Process	In Utero Embryonic Development Chemical Synaptic Transmission Regulation Of Gene Expression Protein Transport Negative Regulation Of Catalytic Activity
Pathways	Neurexins and neuroligins
GWAS	Serum alkaline phosphatase levels ( 33547301 )
Entrez ID	9546
HPRD ID	05038
Ensembl ID	ENSG00000011132
Uniprot IDs	O96018
PDB IDs	2YT7 2YT8 5UWS
GO Terms Enriched among Interactors ?	Serine/threonine Protein Kinase Complex Type I Interferon-mediated Signaling Pathway Interferon-mediated Signaling Pathway Collateral Sprouting Response To External Biotic Stimulus Cell Surface Receptor Signaling Pathway Protein-containing Complex Regulation Of Reactive Oxygen Species Metabolic Process Dendritic Spine Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Learning Or Memory Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Dendrite Development Signal Transduction Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Epidermal Growth Factor Receptor Signaling Pathway Multivesicular Body, Internal Vesicle Lumen Defense Response To Virus Positive Regulation Of Ubiquitin-specific Protease Activity Cognition Negative Regulation Of Signal Transduction Acetylcholine Receptor Activator Activity Developmental Growth Response To Interleukin-1 Plasma Membrane Bounded Cell Projection Organization Regulation Of MiRNA Transcription Negative Regulation Of Signaling Cellular Localization Lipoprotein Particle Regulation Of Programmed Cell Death Positive Regulation Of Protein Import Negative Regulation Of Cell Communication Nervous System Process ERBB Signaling Pathway Phospholipase D Activator Activity Negative Regulation Of Blood Vessel Remodeling Negative Regulation Of Neutrophil Degranulation Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Shc-EGFR Complex Regulation Of MiRNA Metabolic Process Negative Regulation Of Programmed Cell Death PTB Domain Binding Axon Collateral Sprouting In Absence Of Injury Regulation Of Protein Import