LIN52

Name	lin-52 DREAM MuvB core complex component
Structure
Novel Interactors	3 novel interactors: DNAL1 NEK9 RPS6KL1
Interactors	4 interactors: DYRK1A EPM2AIP1 MAGEA6 RBL2
GO Annotations	Cellular Component	Nucleoplasm DRM Complex
	Molecular Function	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription
Pathways	Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
GWAS	Chronotype ( 30696823 ) Macular thickness ( 30535121 ) Mean corpuscular hemoglobin ( 32888494 ) Mean corpuscular volume ( 32888494 ) Red cell distribution width ( 32888494 ) Refractive error ( 32231278 ) Waist-hip ratio ( 28552196 )
Entrez ID	91750
HPRD ID	18708
Ensembl ID	ENSG00000205659
Uniprot IDs	B3KN83 Q52LA3
PDB IDs	4YOO 6C48
GO Terms Enriched among Interactors ?	Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Histone H3T45 Kinase Activity