UNC5A

Name	unc-5 netrin receptor A
Structure
Interactors	3 interactors: DAPK1 MAGED1 NTN1
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection Membrane Neuronal Cell Body Membrane Cell Projection Neuron Projection Membrane Raft
	Molecular Function	Netrin Receptor Activity
	Biological Process	Apoptotic Process Signal Transduction Neuron Projection Development Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway
Pathways	Netrin-1 signaling Netrin mediated repulsion signals Caspase activation via Dependence Receptors in the absence of ligand
GWAS	Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Entrez ID	90249
HPRD ID	12131
Ensembl ID	ENSG00000113763
Uniprot IDs	H0Y8R2 Q6ZN44
PDB IDs	4V2A
GO Terms Enriched among Interactors ?	DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Regulation Of NMDA Receptor Activity Actin Cytoskeleton Cdc42 Protein Signal Transduction Cellular Response To Hydroperoxide Defense Response To Tumor Cell Chemorepulsion Of Axon Substrate-dependent Cell Migration, Cell Extension Anterior/posterior Axon Guidance Mammary Gland Duct Morphogenesis Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Calcium/calmodulin-dependent Protein Kinase Activity Response To Hydroperoxide Glutamatergic Synapse Regulation Of Neurotransmitter Receptor Activity Syntaxin-1 Binding Motor Neuron Migration Regulation Of Glial Cell Migration Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Glial Cell Proliferation