GFM1

Name	G elongation factor mitochondrial 1
Structure
Interactors	3 interactors: RNF10 TRIM55 TRIM63
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Nucleotide Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Hydrolase Activity
	Biological Process	Translation Translational Elongation Mitochondrial Translational Elongation
Pathways	Mitochondrial translation elongation Mitochondrial translation elongation
Diseases	Combined oxidative phosphorylation deficiency (COXPD)
GWAS	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143 ) diarrhoeal disease at age 2 ( 27559109 )
Entrez ID	85476
HPRD ID	07365
Ensembl ID	ENSG00000168827
Uniprot IDs	C9IZ01 E5KND5 Q96RP9
PDB IDs	6VLZ 6VMI 6YDP 6YDW 7A5K
GO Terms Enriched among Interactors ?	Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Protein Ubiquitination Post-translational Protein Modification Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Modification Process Postsynapse To Nucleus Signaling Pathway Transferase Activity Extrinsic Component Of Postsynaptic Density Membrane Microtubule Diapedesis Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Zinc Ion Binding Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation Muscle Atrophy Titin Binding Contractile Muscle Fiber Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation Regulation Of System Process Leukocyte Migration Involved In Inflammatory Response Negative Regulation Of Glycolytic Process Macrophage Migration Innate Immune Response M Band Negative Regulation Of ATP Metabolic Process Protein Metabolic Process Defense Response To Symbiont Defense Response To Other Organism Response To Electrical Stimulus Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Regulation Of Myelination Postsynaptic Signal Transduction Metal Ion Binding Protein Monoubiquitination Regulation Of Glycolytic Process Canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Carbohydrate Catabolic Process Response To Other Organism Protein Autoubiquitination Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Multicellular Organismal Process Protein K63-linked Ubiquitination