PPP1R1B

Name	protein phosphatase 1 regulatory inhibitor subunit 1B
Structure	No pdb structure
Novel Interactors	1 novel interactors: FBXL20
Interactors	9 interactors: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function	Protein Kinase Inhibitor Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Response To Amphetamine DNA-templated Transcription Signal Transduction Negative Regulation Of Female Receptivity Locomotory Behavior Visual Learning Intracellular Signal Transduction Response To Morphine Behavioral Response To Cocaine Cellular Response To Cocaine
Pathways	DARPP-32 events DARPP-32 events
GWAS	Asthma ( 31619474 31959851 ) Estimated glomerular filtration rate ( 31015462 ) Hematocrit ( 32888494 ) Hemoglobin ( 32888494 ) Refractive error ( 32231278 ) Ulcerative colitis ( 20228799 )
Entrez ID	84152
HPRD ID	05097
Ensembl ID	ENSG00000131771
Uniprot IDs	B3KVQ9 Q9UD71
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Protein Kinase CK2 Complex Regulation Of Macroautophagy Neuromuscular Junction Protein Serine Kinase Activity Regulation Of Proteolysis Regulation Of Autophagy Regulation Of Protein Catabolic Process Protein Serine/threonine Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Regulation Of Cell Communication Regulation Of Signaling PcG Protein Complex Modulation Of Chemical Synaptic Transmission Protein Kinase Activity Macromolecule Catabolic Process Regulation Of Protein Export From Nucleus Regulation Of Proteasomal Protein Catabolic Process Glutamatergic Synapse Presynapse Hsp90 Protein Binding Kinase Activity Central Nervous System Neuron Development Protein Catabolic Process Double-strand Break Repair Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Glucose Metabolic Process Rhythmic Process Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synapse Organization Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Protein Catabolic Process At Presynapse, Modulating Synaptic Transmission Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Establishment Of Protein Localization Anatomical Structure Formation Involved In Morphogenesis Regulation Of Chromosome Separation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Macromolecule Metabolic Process Acetylcholine Receptor Activator Activity Regulation Of Cellular Component Organization Regulation Of Neurotransmitter Secretion Cerebral Cortex Development Negative Regulation Of Catabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Apoptotic Process Regulation Of Apoptotic Signaling Pathway