IFRD2

Name	interferon related developmental regulator 2
Structure	No pdb structure
Interactors	8 interactors: APP JRK MDFI NEDD4L OAS3 OGT POT1 UBE2O
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Protein Binding Translation Repressor Activity Ribosome Binding
	Biological Process	Regulation Of Translation Wnt Signaling Pathway Negative Regulation Of Translation Fat Cell Differentiation Adipose Tissue Development
GWAS	Body mass index ( 26426971 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) High light scatter reticulocyte count ( 27863252 32888494 ) High light scatter reticulocyte percentage of red cells ( 27863252 32888494 ) Immature fraction of reticulocytes ( 27863252 32888494 ) Mean reticulocyte volume ( 32888494 ) Reticulocyte count ( 27863252 32888494 ) Reticulocyte fraction of red cells ( 27863252 32888494 ) Sleep duration (short sleep) ( 30846698 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 )
Entrez ID	7866
HPRD ID	04101
Ensembl ID	ENSG00000214706
Uniprot IDs	Q12894
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Amyloid-beta Complex Regulation Of Wnt Signaling Pathway Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Synapse Organization Positive Regulation Of Chemokine Production Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Negative Regulation Of Chemokine (C-X-C Motif) Ligand 9 Production Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Monoubiquitination Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Regulation Of Signal Transduction Regulation Of Purine Nucleotide Metabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Chemokine Production Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Negative Regulation Of Macromolecule Biosynthetic Process Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Negative Regulation Of Biosynthetic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Low-density Lipoprotein Particle Mediated Signaling Regulation Of Signaling MDA-5 Signaling Pathway Negative Regulation Of IP-10 Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production 2'-5'-oligoadenylate Synthetase Activity