SCG2

Name	secretogranin II
Structure	No pdb structure
Interactors	5 interactors: ATRIP NRIP1 TUBB4B UBQLN1 UBQLN4
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule Dense Core Granule Neuronal Dense Core Vesicle
	Molecular Function	Cytokine Activity Protein Binding Chemoattractant Activity
	Biological Process	MAPK Cascade Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Endothelial Cell Proliferation Inflammatory Response Protein Secretion Intracellular Signal Transduction Endothelial Cell Migration Eosinophil Chemotaxis Positive Chemotaxis Induction Of Positive Chemotaxis Negative Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
GWAS	Airway wall thickness ( 25517131 ) Depression in smokers ( 30219690 ) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 ) Fasting plasma glucose ( 32902719 ) Night sleep phenotypes ( 27126917 ) Osteoporosis-related phenotypes ( 20200953 ) Recurrent major depressive disorder x sex interaction ( 34099189 ) Response to hepatitis C treatment ( 22095909 ) Sodium levels ( 29403010 ) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858 ) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 )
Entrez ID	7857
HPRD ID	06762
Ensembl ID	ENSG00000171951
Uniprot IDs	P13521
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Polyubiquitin Modification-dependent Protein Binding Ovarian Follicle Rupture Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Cellular Response To Stress Autophagosome Nuclear Proteasome Complex ATR-ATRIP Complex Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Autophagosome Maturation Regulation Of Double-strand Break Repair Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy Cytosolic Proteasome Complex Regulation Of DNA Repair Autophagy K48-linked Polyubiquitin Modification-dependent Protein Binding Nuclear Retinoid X Receptor Binding Ovulation Nuclear Glucocorticoid Receptor Binding Nuclear Retinoic Acid Receptor Binding MHC Class I Protein Binding Response To Stress Aggrephagy Positive Regulation Of ERAD Pathway Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Autophagy Regulation Of Autophagosome Maturation