SLN

Name	sarcolipin
Structure
Novel Interactors	1 novel interactors: DDX10
Interactors	7 interactors: ATP2A1 KASH5 LMNA PLN PTPN11 SYNE4 TMEM79
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Enzyme Regulator Activity ATPase Binding
	Biological Process	Calcium Ion Transport Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Calcium Ion Transport Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Calcium Ion Import Positive Regulation Of Cold-induced Thermogenesis Regulation Of Relaxation Of Muscle Positive Regulation Of Protein Depolymerization Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways	Ion homeostasis Ion transport by P-type ATPases
GWAS	No GWAS studies recorded
Entrez ID	6588
HPRD ID	03729
Ensembl ID	ENSG00000170290
Uniprot IDs	A0A158RFT9 O00631
PDB IDs	1JDM
GO Terms Enriched among Interactors ?	Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Meiotic Nuclear Membrane Microtubule Tethering Complex Relaxation Of Muscle Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATP-dependent Activity Regulation Of System Process Nuclear Envelope Nuclear Outer Membrane Sarcoplasmic Reticulum Membrane Regulation Of Muscle System Process Regulation Of Intracellular Transport Maintenance Of Mitochondrion Location Calcium-dependent ATPase Activity Sarcoplasmic Reticulum Regulation Of Transmembrane Transporter Activity Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Relaxation Of Skeletal Muscle H Zone Regulation Of Cardiac Muscle Contraction Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of Striated Muscle Contraction Regulation Of Monoatomic Ion Transmembrane Transporter Activity DNA Double-strand Break Attachment To Nuclear Envelope Chromosome Localization Structural Constituent Of Nuclear Lamina Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Intestinal Epithelial Cell Migration Meiotic Spindle Pole Organelle Localization Developmental Process Negative Regulation Of Multicellular Organismal Process Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Cellular Localization Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Cerebellar Cortex Formation Cuticle Development Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Circadian Sleep/wake Cycle Process Negative Regulation Of Glucocorticoid Secretion Anterior Head Development