SLC9A5

Name	solute carrier family 9 member A5
Structure	No pdb structure
Interactors	5 interactors: ARRB1 ARRB2 CHP1 CHP2 RACK1
GO Annotations	Cellular Component	Endosome Plasma Membrane Focal Adhesion Membrane Dendritic Spine Membrane Cell Projection Neuron Spine Synapse Postsynaptic Membrane Recycling Endosome Membrane Anchoring Junction Synaptic Membrane
	Molecular Function	Protein Binding Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Arrestin Family Protein Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Regulation Of PH Sodium Ion Transmembrane Transport Regulation Of Intracellular PH Transmembrane Transport Potassium Ion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport
Pathways	Sodium/Proton exchangers
GWAS	A body shape index ( 34021172 ) High density lipoprotein cholesterol levels ( 33339817 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Refractive error ( 32231278 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	6553
HPRD ID	02723
Ensembl ID	ENSG00000135740
Uniprot IDs	Q14940
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Angiotensin Receptor Binding Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Transport Positive Regulation Of Phosphate Metabolic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Protein Ubiquitination Desensitization Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Post-translational Protein Modification Negative Adaptation Of Signaling Pathway Regulation Of Phosphatase Activity G Protein-coupled Receptor Internalization Regulation Of Phosphorus Metabolic Process Regulation Of Transport Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Regulation Of Protein Modification Process Regulation Of DNA-binding Transcription Factor Activity Molecular Adaptor Activity Regulation Of Protein Ubiquitination Regulation Of Dephosphorylation Regulation Of Intracellular Signal Transduction Positive Regulation Of Receptor Internalization Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Transport Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Endocytosis Positive Regulation Of Establishment Of Protein Localization Protein Transport Negative Regulation Of Interleukin-6 Production Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Protein Modification Process Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Protein Phosphorylation Enzyme Binding Regulation Of Protein Import Into Nucleus Establishment Of Protein Localization Regulation Of Phosphorylation Receptor Internalization Regulation Of Signal Transduction Clathrin-coated Pit Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Protein Localization Regulation Of Protein Transport Endocytic Vesicle Membrane G Protein-coupled Receptor Binding Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Receptor Internalization