GAREM1

Name	GRB2 associated regulator of MAPK1 subtype 1
Structure
Interactors	5 interactors: CFTR CRK CRKL GRAP2 NCK2
GO Annotations	Cellular Component	Plasma Membrane
	Molecular Function	Protein Binding Proline-rich Region Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Multicellular Organism Growth Positive Regulation Of Cell Division Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Epidermal Growth Factor Stimulus
GWAS	Breast cancer ( 29059683 ) Left ventricular internal dimension in diastole ( 29403010 ) Left ventricular internal dimension in systole ( 29403010 )
Entrez ID	64762
HPRD ID	12685
Ensembl ID	ENSG00000141441
Uniprot IDs	Q9H706
PDB IDs	2DKZ
GO Terms Enriched among Interactors ?	Phosphotyrosine Residue Binding Helper T Cell Diapedesis Cerebellar Neuron Development Receptor Tyrosine Kinase Binding Signaling Adaptor Activity Diapedesis Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Receptor Clustering Reelin-mediated Signaling Pathway Postsynaptic Specialization Assembly Regulation Of Receptor Clustering Positive Regulation Of Rac Protein Signal Transduction Postsynaptic Specialization Organization Signaling Receptor Complex Adaptor Activity Regulation Of Rac Protein Signal Transduction T Cell Migration Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Dendrite Development Central Nervous System Neuron Development Regulation Of T Cell Migration Regulation Of Cell Adhesion Mediated By Integrin Ephrin Receptor Signaling Pathway Lymphocyte Migration Regulation Of Substrate Adhesion-dependent Cell Spreading Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Protein Localization Regulation Of Lymphocyte Migration Hippocampus Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Scaffold Protein Binding Response To Transforming Growth Factor Beta Positive Regulation Of Small GTPase Mediated Signal Transduction Neuromuscular Junction Ras Protein Signal Transduction Positive Regulation Of Cell Adhesion Cerebral Cortex Development Regulation Of Cellular Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Protein Localization To Membrane Establishment Of Cell Polarity Regulation Of Dendrite Development Regulation Of Cell Communication Regulation Of Signaling Mononuclear Cell Migration Positive Regulation Of Cell Communication Positive Regulation Of Anion Channel Activity Positive Regulation Of Signaling