RTN1

Name	reticulon 1
Structure	No pdb structure
Novel Interactors	1 novel interactors: KIAA0586
Interactors	15 interactors: ADRB2 BCL2L1 CCR4 CHRM5 DRD2 F2RL1 FGFR1 FHIP1B HDAC8 LMNA NDRG1 PLEKHF2 SDCBP SPAST UGCG
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Postsynaptic Density Membrane Nuclear Body Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding
	Biological Process	Brain Development Neuron Differentiation Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation Endoplasmic Reticulum Tubular Network Membrane Organization
GWAS	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 ) Broad depression or schizophrenia ( 30626913 ) Putamen volume ( 31530798 ) Schizophrenia ( 30285260 )
Entrez ID	6252
HPRD ID	02921
Ensembl ID	ENSG00000139970
Uniprot IDs	A8K3B9 A8MT72 Q16799
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Protein-containing Complex Disassembly Regulation Of Organelle Organization Orbitofrontal Cortex Development G Protein-coupled Receptor Activity Endosome To Lysosome Transport Positive Regulation Of MAPK Cascade Regulation Of Cytokinesis Nuclear Membrane Interneuron Migration Regulation Of Cellular Component Organization Regulation Of Growth Lysosomal Transport Regulation Of System Process Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Dephosphorylation Dopamine Transport Positive Regulation Of Secretion Positive Regulation Of Secretion By Cell Positive Regulation Of Protein Depolymerization Membrane Organization Regulation Of MAPK Cascade Signal Transduction Acid Secretion Monoamine Transport Neuron Migration G-protein Alpha-subunit Binding Positive Regulation Of Cellular Component Organization Vesicle-mediated Transport Regulation Of Extrinsic Apoptotic Signaling Pathway Vacuolar Transport Regulation Of Blood Pressure Regulation Of Mesenchymal Cell Proliferation Temperature Homeostasis Regulation Of Cell Division G Protein-coupled Receptor Signaling Pathway Potassium Channel Regulator Activity Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Blood Pressure Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Release Of Cytochrome C From Mitochondria Cell Development Apoptotic Process In Bone Marrow Cell Negative Regulation Of Insulin Secretion Positive Regulation Of Cytokinesis Negative Regulation Of Peptide Secretion Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream