PHF12

Name	PHD finger protein 12
Structure
Novel Interactors	1 novel interactors: NUFIP2
Interactors	7 interactors: ATP6V0D2 BRCA1 H3-4 HDAC1 MORF4L1 SHANK3 SIN3A
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Repressor Complex Sin3-type Complex
	Molecular Function	Transcription Corepressor Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
GWAS	No GWAS studies recorded
Entrez ID	57649
HPRD ID	15123
Ensembl ID	ENSG00000109118
Uniprot IDs	Q96QT6
PDB IDs	2L9S 2LKM 8BPA 8BPB 8BPC 8C60
GO Terms Enriched among Interactors ?	Sin3-type Complex Chromatin Organization Heterochromatin Formation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone Deacetylase Complex Forebrain Neuron Differentiation Condensed Nuclear Chromosome Epigenetic Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Heterochromatin P53 Binding Neuron Differentiation Transcription Repressor Complex Cellular Response To Tert-butyl Hydroperoxide Response To Methylglyoxal Regulation Of Stem Cell Population Maintenance Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Krueppel-associated Box Domain Binding Guanylate Kinase-associated Protein Clustering Plasma Membrane Proton-transporting V-type ATPase Complex Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Binding Regulation Of Cell Cycle G2/M Phase Transition Protein Lysine Delactylase Activity Fungiform Papilla Formation Nucleosome Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation BRCA1-B Complex Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Via Homologous Recombination Protein Decrotonylase Activity Histone Decrotonylase Activity Spermatogonial Cell Division Central Nervous System Neuron Differentiation Synaptic Receptor Adaptor Activity Negative Regulation Of Cytoskeleton Organization Cellular Response To Indole-3-methanol Positive Regulation Of Developmental Process Regulation Of Developmental Process Hair Follicle Placode Formation