ADGRB2

Name	adhesion G protein-coupled receptor B2
Structure
Novel Interactors	2 novel interactors: B4GALT2 HDAC5
Interactors	9 interactors: ARHGAP1 DLG4 GABPB1 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Glutamatergic Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis Calcineurin-NFAT Signaling Cascade Positive Regulation Of Synapse Assembly
GWAS	Asthma ( 31959851 ) Intraocular pressure ( 29617998 29785010 ) Smoking status (ever vs never smokers) ( 30643258 ) Walking pace ( 33128006 )
Entrez ID	576
HPRD ID	04063
Ensembl ID	ENSG00000121753
Uniprot IDs	A2A3C1 O60241
PDB IDs	8OEK
GO Terms Enriched among Interactors ?	Vocalization Behavior Ionotropic Glutamate Receptor Binding Learning Synaptic Receptor Adaptor Activity Social Behavior Learning Or Memory Associative Learning Cognition SH3 Domain Binding Dendritic Spine Morphogenesis Dendritic Spine Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Ionotropic Glutamate Receptor Signaling Pathway Excitatory Synapse Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Ligand-gated Ion Channel Signaling Pathway Neuron Projection Organization Postsynapse Organization Postsynaptic Membrane Neuromuscular Process Controlling Balance Modulation Of Excitatory Postsynaptic Potential Glutamate Receptor Signaling Pathway Postsynaptic Density Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis P2Y1 Nucleotide Receptor Binding Protein Localization To Synapse Determination Of Affect Somatostatin Receptor Binding Scaffold Protein Binding Negative Regulation Of Endothelial Cell Migration Neuron Projection Neuromuscular Junction Protein Localization To Cell Junction PDZ Domain Binding Endothelial Tube Lumen Extension System Process Negative Regulation Of Endocytic Recycling Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Nervous System Process Lactose Synthase Activity Structural Constituent Of Postsynaptic Density Regulation Of Nervous System Process Regulation Of Membrane Potential Neuromuscular Process Syntrophin Complex N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity