SUPT20H

Name	SPT20 homolog, SAGA complex component
Structure
Novel Interactors	1 novel interactors: FOXH1
Interactors	10 interactors: AQP2 ATXN1 AURKA H3-4 LCOR MAP3K7 MAPK1 MAPK14 STAT3 UBQLN4
GO Annotations	Cellular Component	SAGA Complex Nucleus SAGA-type Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of DNA Repair Regulation Of Transcription By RNA Polymerase II Autophagy Gastrulation Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription
Pathways	HATs acetylate histones
GWAS	Platelet distribution width ( 32888494 )
Entrez ID	55578
HPRD ID	10135
Ensembl ID	ENSG00000102710
Uniprot IDs	A8K8L1 Q8NEM7 R4GND2
PDB IDs	7KTR 7KTS 8H7G
GO Terms Enriched among Interactors ?	MAP Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Enzyme-linked Receptor Protein Signaling Pathway Cellular Response To Cytokine Stimulus Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Response To Peptide Response To Cytokine Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Tumor Necrosis Factor Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Metabolic Process Protein Serine Kinase Activity Response To Tumor Necrosis Factor Phosphorylation Protein Serine/threonine Kinase Activity Cytokine-mediated Signaling Pathway P38MAPK Cascade Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Population Proliferation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Differentiation Astrocyte Differentiation Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway DNA-binding Transcription Factor Binding Insulin-like Growth Factor Receptor Signaling Pathway Protein Kinase Activity Positive Regulation Of Erythrocyte Differentiation Lipopolysaccharide-mediated Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Biological Quality Carbohydrate Transmembrane Transport Regulation Of Primary Metabolic Process MAPK Cascade Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Nucleus Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Locomotion Carbohydrate Transport Kinase Activity Regulation Of Erythrocyte Differentiation Canonical NF-kappaB Signal Transduction Nucleoplasm Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Transcription By RNA Polymerase II Regulation Of Signal Transduction Response To Growth Factor