TRIM36

Name	tripartite motif containing 36
Structure
Interactors	11 interactors: BTRC EIF4A2 GLRX3 GRB7 TRAF3IP3 UBC UBE2D2 UBE2H ZMAT2 ZNF417 ZNF587
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Alpha-tubulin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Cytokinesis Spindle Organization Acrosome Reaction Regulation Of Cell Cycle Regulation Of Microtubule Cytoskeleton Organization
Pathways	Antigen processing: Ubiquitination & Proteasome degradation
GWAS	Diastolic blood pressure ( 27618452 27841878 28739976 30487518 ) Diastolic blood pressure (cigarette smoking interaction) ( 29455858 ) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962 ) Left-handedness ( 32989287 ) Malaria ( 31844061 ) Mean arterial pressure ( 30487518 ) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962 ) Systolic blood pressure ( 27618452 27841878 28739976 ) Systolic blood pressure (cigarette smoking interaction) ( 29455858 )
Entrez ID	55521
HPRD ID	15554
Ensembl ID	ENSG00000152503
Uniprot IDs	E9PBG3 Q4R1Q4 Q9NQ86
PDB IDs	7QS4
GO Terms Enriched among Interactors ?	Protein K48-linked Ubiquitination Negative Regulation Of RNA-dependent RNA Polymerase Activity Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Protein Phosphorylated Amino Acid Binding Post-translational Protein Modification