TRMT61B

Name	tRNA methyltransferase 61B
Structure
Novel Interactors	1 novel interactors: CLIP4
Interactors	3 interactors: FAM9B IRF7 PPP2CB
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix TRNA (m1A) Methyltransferase Complex
	Molecular Function	Protein Binding Methyltransferase Activity TRNA (adenine) Methyltransferase Activity RRNA (adenine) Methyltransferase Activity Transferase Activity MRNA (adenine-N1-)-methyltransferase Activity TRNA (adenine(58)-N1)-methyltransferase Activity
	Biological Process	MRNA Processing TRNA Processing TRNA Methylation RRNA Methylation Methylation Mitochondrial TRNA Processing
Pathways	tRNA modification in the mitochondrion Mitochondrial mRNA modification
GWAS	Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143 ) Intraocular pressure ( 29617998 )
Entrez ID	55006
HPRD ID	07935
Ensembl ID	ENSG00000171103
Uniprot IDs	F8WDR2 Q9BVS5
PDB IDs	2B25
GO Terms Enriched among Interactors ?	Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway MDA-5 Signaling Pathway Establishment Of Viral Latency Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Macrophage Apoptotic Process