ATP6V1G2

Name	ATPase H+ transporting V1 subunit G2
Structure	No pdb structure
Interactors	3 interactors: ATP6V1E1 ATP6V1E2 USP20
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Cytosol Membrane Vacuolar Proton-transporting V-type ATPase Complex Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Melanosome Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding ATP Hydrolysis Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Monoatomic Ion Transport Regulation Of Macroautophagy Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs	Tiludronic acid
GWAS	Asthma ( 31619474 ) Asthma (childhood onset) ( 31619474 ) Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Inflammatory bowel disease ( 28067908 ) LDL cholesterol levels ( 32203549 ) Malaria ( 31844061 ) Monocyte percentage of white cells ( 32888494 ) Myositis ( 26291516 ) Ulcerative colitis ( 28067908 )
Entrez ID	534
HPRD ID	06030
Ensembl ID	ENSG00000213760
Uniprot IDs	O95670 Q6NVJ2
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Proton-transporting Two-sector ATPase Complex, Catalytic Domain Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Autophagy Proton Transmembrane Transport Regulation Of Macroautophagy Proton-transporting Two-sector ATPase Complex Vacuolar Proton-transporting V-type ATPase, V1 Domain Inorganic Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Synaptic Vesicle Lumen Acidification Inorganic Cation Transmembrane Transport Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Clathrin-coated Vesicle Membrane