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MVD

Name mevalonate diphosphate decarboxylase
Structure PDB 3D4J
Novel Interactors 1 novel interactors: TUBB3
Interactors 5 interactors: BTAF1 EEF1G EIF4EBP1 GNB5 HSPA9
GO Annotations Cellular Component
  • Cytoplasm
  • Peroxisome
  • Cytosol
Molecular Function
  • Nucleotide Binding
  • Diphosphomevalonate Decarboxylase Activity
  • ATP Binding
  • Lyase Activity
  • Carboxy-lyase Activity
  • Hsp70 Protein Binding
  • Protein Homodimerization Activity
Biological Process
  • Lipid Metabolic Process
  • Steroid Biosynthetic Process
  • Cholesterol Biosynthetic Process
  • Steroid Metabolic Process
  • Cholesterol Metabolic Process
  • Positive Regulation Of Cell Population Proliferation
  • Isoprenoid Biosynthetic Process
  • Sterol Biosynthetic Process
  • Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway
Pathways
  • Cholesterol biosynthesis
  • Activation of gene expression by SREBF (SREBP)
  • Synthesis of dolichyl-phosphate
GWAS
  • Feeling fed-up ( 29500382 )
  • Hair color ( 26926045 )
Entrez ID 4597
HPRD ID 04454
Ensembl ID ENSG00000167508
Uniprot IDs P53602
PDB IDs 3D4J
GO Terms Enriched among Interactors ?
  • Negative Regulation Of Chromatin Binding
  • Netrin Receptor Binding
  • GTPase Activator Complex
  • G-protein Gamma-subunit Binding
  • Dark Adaptation
  • Light Adaption
  • Negative Regulation Of Hematopoietic Stem Cell Differentiation
  • Dorsal Root Ganglion Development

© Madhavi K. Ganapathiraju 2012-2026