MAK

Name	male germ cell associated kinase
Structure	No pdb structure
Interactors	9 interactors: ANAPC11 APP FBXO7 FZR1 NDUFB7 PPP2CB SERINC1 SLAMF7 SND1
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Midbody Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Mitotic Spindle
	Molecular Function	Nucleotide Binding Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Spermatogenesis Cell Differentiation Intracellular Signal Transduction Intraciliary Transport Photoreceptor Cell Maintenance Positive Regulation Of DNA-templated Transcription Protein Autophosphorylation Cilium Assembly Negative Regulation Of Non-motile Cilium Assembly Non-motile Cilium Assembly
GWAS	Menopause (age at onset) ( 26414677 ) Recurrent major depressive disorder ( 29317602 ) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261 )
Entrez ID	4117
HPRD ID	01101
Ensembl ID	ENSG00000111837
Uniprot IDs	A0A140VK28 A0A6Q8PG01 A0A6Q8PH30 F8VBW7 P20794 Q8IXN4
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Response To Lead Ion Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Catabolic Process Anaphase-promoting Complex Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Protein K11-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Polyubiquitination Regulation Of Cell Cycle Process Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite RNAi Effector Complex Regulation Of Meiotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition G Protein-coupled Receptor Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Catabolic Process Ubiquitin-like Ligase-substrate Adaptor Activity Lewy Body Core Protein K48-linked Ubiquitination Regulation Of Cell Cycle Phase Transition DNA Synthesis Involved In Mitotic DNA Replication Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway