FOXA3

Name	forkhead box A3
Structure
Novel Interactors	1 novel interactors: MET
Interactors	5 interactors: ALX4 HMGB1 PPARA TLE1 TLE2
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Actin Cytoskeleton
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Glucose Homeostasis Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spermatogenesis Cellular Response To Starvation Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Homeostasis
Pathways	Regulation of gene expression in beta cells
GWAS	Asthma ( 31959851 32296059 ) Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143 ) Coronary artery disease ( 29212778 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Sum eosinophil basophil counts ( 27863252 )
Entrez ID	3171
HPRD ID	03802
Ensembl ID	ENSG00000170608
Uniprot IDs	P55318
PDB IDs	1VTN
GO Terms Enriched among Interactors ?	Transcription Corepressor Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Programmed Cell Death DNA-binding Transcription Factor Binding Regulation Of RNA Metabolic Process Transcription Regulator Complex Positive Regulation Of Glucose Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Chemotaxis Positive Regulation Of Binding Regulation Of Carbohydrate Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Animal Organ Development Negative Regulation Of RNA Biosynthetic Process Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Regulation Of Gene Expression Regulation Of Glucose Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Hepatocyte Growth Factor Receptor Activity Negative Regulation Of Signal Transduction Positive Regulation Of Transformation Of Host Cell By Virus Animal Organ Morphogenesis Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Endothelial Cell Migration Developmental Process Negative Regulation Of Apoptotic Cell Clearance Anatomical Structure Morphogenesis Negative Regulation Of Cell Communication Negative Regulation Of Signaling Positive Regulation Of Macromolecule Metabolic Process C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Positive Regulation Of Mismatch Repair Regulation Of Signal Transduction Positive Regulation Of Chemotaxis Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Epidermis Development