GLRA2

Name	glycine receptor alpha 2
Structure
Novel Interactors	1 novel interactors: POLA1
Interactors	5 interactors: BAG6 DDX24 GDI2 PSD SEC23A
GO Annotations	Cellular Component	Plasma Membrane Membrane Chloride Channel Complex Cell Projection Synapse Postsynaptic Membrane Glycinergic Synapse GABA-ergic Synapse Postsynaptic Specialization Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Monoatomic Ion Channel Activity Extracellular Ligand-gated Monoatomic Ion Channel Activity Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Chloride Channel Activity Glycine Binding Extracellularly Glycine-gated Chloride Channel Activity Transmitter-gated Monoatomic Ion Channel Activity Glycine-gated Chloride Ion Channel Activity Metal Ion Binding Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Monoatomic Ion Transport Chloride Transport Neuropeptide Signaling Pathway Monoatomic Ion Transmembrane Transport Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Excitatory Postsynaptic Potential Cellular Response To Amino Acid Stimulus Cellular Response To Zinc Ion Cellular Response To Ethanol Chloride Transmembrane Transport
Pathways	Neurotransmitter receptors and postsynaptic signal transmission Neurotransmitter receptors and postsynaptic signal transmission
Drugs	Glycine Lindane Picrotoxin Ethanol Memantine Taurine
GWAS	No GWAS studies recorded
Entrez ID	2742
HPRD ID	02379
Ensembl ID	ENSG00000101958
Uniprot IDs	P23416
PDB IDs	5BKF 5BKG 7KUY 7L31
GO Terms Enriched among Interactors ?	Rab GDP-dissociation Inhibitor Activity Negative Regulation Of Protein Localization To Cilium Mitotic DNA Replication Initiation Lagging Strand Elongation DNA Synthesis Involved In UV-damage Excision Repair Leading Strand Elongation Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Maintenance Of Unfolded Protein BAT3 Complex Alpha DNA Polymerase:primase Complex COPII-coated Vesicle Budding DNA Replication, Synthesis Of Primer