MAST3

Name	microtubule associated serine/threonine kinase 3
Structure
Novel Interactors	4 novel interactors: FOXP2 GDF15 MYCBP2 SIM2
Interactors	2 interactors: CNTNAP4 PTEN
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Cytoskeleton Organization Intracellular Signal Transduction
GWAS	A body shape index ( 34021172 ) Adult body size ( 32376654 ) Alanine aminotransferase levels ( 33547301 ) Body fat mass ( 28552196 ) Eosinophil percentage of white cells ( 32888494 ) Glycine levels ( 30837465 ) Liver enzyme levels (alanine transaminase) ( 33972514 ) Mental health study participation (completed survey) ( 31263887 ) Number of sexual partners ( 30643258 ) Percent liver fat ( 34128465 ) Red cell distribution width ( 32888494 ) Urate levels ( 31578528 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 ) Walking pace ( 33128006 )
Entrez ID	23031
HPRD ID	19403
Ensembl ID	ENSG00000099308
Uniprot IDs	A0A8I5KST9 A0A8V8TLL8 A0A8V8TMW0 O60307
PDB IDs	1V9V 3KHF
GO Terms Enriched among Interactors ?	Central Nervous System Neuron Axonogenesis Regulation Of Growth Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Developmental Growth Regulation Of Developmental Growth Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Lung Development Response To Metformin Putamen Development Caudate Nucleus Development Central Nervous System Myelin Maintenance Circadian Rhythm Rhythmic Synaptic Transmission Regulation Of Grooming Behavior Locomotor Rhythm Regulation Of Cell Junction Assembly Cell Projection Morphogenesis Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Cellular Response To Electrical Stimulus Learning Or Memory Negative Regulation Of Growth Regulation Of Locomotion Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Neuron Projection Morphogenesis Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Negative Regulation Of Cell Size Presynaptic Membrane Organization Schmidt-Lanterman Incisure Anaphase-promoting Complex Binding Postsynaptic Density Assembly Rhythmic Process Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Axonogenesis Presynaptic Membrane Assembly Nervous System Process GDF15-GFRAL Signaling Pathway Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of Appetite Negative Regulation Of Growth Hormone Receptor Signaling Pathway