SKA3

Name	spindle and kinetochore associated complex subunit 3
Structure
Interactors	6 interactors: APP AURKB LRRK2 NDC80 SPC24 ZDHHC17
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Outer Kinetochore Chromosome Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Spindle Microtubule Mitotic Spindle Meiotic Spindle SKA Complex
	Molecular Function	Protein Binding Microtubule Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Spindle Assembly Involved In Female Meiosis Chromosome Segregation Mitotic Metaphase Chromosome Alignment Regulation Of Microtubule Polymerization Or Depolymerization Establishment Of Meiotic Spindle Orientation Cell Division Metaphase Chromosome Alignment Attachment Of Mitotic Spindle Microtubules To Kinetochore Negative Regulation Of Mitotic Spindle Assembly Checkpoint Signaling
GWAS	No GWAS studies recorded
Entrez ID	221150
HPRD ID	10706
Ensembl ID	ENSG00000165480
Uniprot IDs	Q8IX90
PDB IDs	4AJ5
GO Terms Enriched among Interactors ?	Attachment Of Spindle Microtubules To Kinetochore Regulation Of Mitotic Sister Chromatid Separation Ndc80 Complex Regulation Of Chromosome Separation Cellular Response To Manganese Ion Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Intracellular Signal Transduction Regulation Of Sister Chromatid Segregation Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Regulation Of Mitotic Nuclear Division Regulation Of Cellular Component Organization Response To Manganese Ion Regulation Of Chromosome Segregation Regulation Of Mitotic Cell Cycle Regulation Of Nuclear Division Golgi-associated Vesicle Cellular Response To Catecholamine Stimulus Response To Catecholamine Chromosome, Centromeric Region Negative Regulation Of Mitotic Cell Cycle Phase Transition Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Positive Regulation Of Cell Cycle Checkpoint Outer Kinetochore Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Signal Transduction Negative Regulation Of Cell Cycle Phase Transition Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Organization Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Microtubule Binding Neuron Projection Morphogenesis Negative Regulation Of Cell Cycle Process Negative Regulation Of Mitotic Nuclear Division Cell Projection Morphogenesis Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Regulation Of Synapse Organization Regulation Of Intracellular Signal Transduction Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Cell Cycle G2/M Phase Transition Negative Regulation Of Cell Cycle Regulation Of Cell Cycle