F13B

Name	coagulation factor XIII B chain
Structure
Novel Interactors	1 novel interactors: PTPRC
Interactors	2 interactors: F13A1 FGG
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Transferase Complex
	Biological Process	Blood Coagulation Hemostasis Blood Coagulation, Fibrin Clot Formation
Pathways	Common Pathway of Fibrin Clot Formation
Drugs	Zinc Catridecacog Thrombin Human thrombin Zinc acetate
Diseases	Factor XIII deficiency
GWAS	Age-related macular degeneration ( 23536807 ) Erectile dysfunction in type 1 diabetes ( 22704111 ) Lupus nephritis in systemic lupus erythematosus ( 24925725 )
Entrez ID	2165
HPRD ID	00605
Ensembl ID	ENSG00000143278
Uniprot IDs	P05160
PDB IDs	8CMT 8CMU
GO Terms Enriched among Interactors ?	Blood Coagulation, Fibrin Clot Formation Protein Activation Cascade Platelet Alpha Granule Lumen Coagulation Blood Coagulation Hemostasis Blood Microparticle Plasma Membrane Raft Distribution Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Migration Membrane Microdomain DN2 Thymocyte Differentiation Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Protein Maturation Extracellular Matrix Regulation Of Body Fluid Levels Protein-glutamine Gamma-glutamyltransferase Activity Positive Regulation Of Cell-cell Adhesion Signaling Receptor Binding Regulation Of Apoptotic Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Plasminogen Activation Fibrinogen Complex External Side Of Plasma Membrane Negative Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Microglial Cell Activation Positive Regulation Of Isotype Switching To IgG Isotypes Protein Tyrosine Kinase Inhibitor Activity Positive Regulation Of Gamma-delta T Cell Activation Membrane Raft Distribution Gamma-delta T Cell Differentiation Membrane Raft Localization Bleb Bone Marrow Development Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Gamma-delta T Cell Differentiation Transferase Complex Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of MAPK Cascade Positive Thymic T Cell Selection Negative Thymic T Cell Selection Negative T Cell Selection Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion