GLIPR2

Name	GLI pathogenesis related 2
Structure
Novel Interactors	2 novel interactors: CDKN2A ELAVL2
Interactors	3 interactors: FBXO7 KRTAP10-3 PNMA5
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Membrane Extracellular Exosome
	Molecular Function	Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Sexual Reproduction Positive Regulation Of ERK1 And ERK2 Cascade
Drugs	L-cysteic acid
GWAS	Bipolar disorder (inflammation and infection response interaction) ( 25781172 )
Entrez ID	152007
HPRD ID	06187
Ensembl ID	ENSG00000122694
Uniprot IDs	A0A087WUM5 A0A088AWP7 Q5VZR0 Q9H4G4
PDB IDs	1SMB 4AIW 5VHG
GO Terms Enriched among Interactors ?	Negative Regulation Of Lymphocyte Differentiation Autophagy Of Mitochondrion Ligase Inhibitor Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Negative Regulation Of Hemopoiesis Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Lymphocyte Activation Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Leukocyte Activation Senescence-associated Heterochromatin Focus Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Lewy Body Core Regulation Of Lymphocyte Differentiation Negative Regulation Of Cell Activation Negative Regulation Of Immature T Cell Proliferation Mitochondrial Depolarization Oncogene-induced Cell Senescence Positive Regulation Of Apoptotic Process Involved In Morphogenesis Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Apoptotic Process Involved In Development Somatic Stem Cell Division Protein Localization To Nucleolus Negative Regulation Of Cyclin-dependent Protein Kinase Activity MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Polyubiquitination Ubiquitin Ligase Inhibitor Activity Autophagy Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Cell Development Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Cell Cycle Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Stability Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator