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MYSM1

Name Myb like, SWIRM and MPN domains 1
Structure PDB 2CU7
Novel Interactors 1 novel interactors: HOOK1
Interactors 3 interactors: H2AC20 MPP7 STING1
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Cytoplasm
  • Protein-containing Complex
Molecular Function
  • DNA Binding
  • Transcription Coactivator Activity
  • Protein Binding
  • Peptidase Activity
  • Metallopeptidase Activity
  • Hydrolase Activity
  • Histone Binding
  • Metal Ion Binding
  • Metal-dependent Deubiquitinase Activity
  • Histone H2A Deubiquitinase Activity
Biological Process
  • Immune System Process
  • Chromatin Organization
  • Chromatin Remodeling
  • Proteolysis
  • Regulation Of Cell Migration
  • Pigmentation
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Regulation Of Hair Follicle Development
  • Regulation Of Hemopoiesis
Pathways
  • Metalloprotease DUBs
GWAS
  • Diabetic retinopathy ( 21310492 )
  • Metabolite levels ( 23823483 )
  • Nickel levels ( 26025379 )
  • Night sleep phenotypes ( 27126917 )
Entrez ID 114803
HPRD ID 13903
Ensembl ID ENSG00000162601
Uniprot IDs A0A590UJW2 Q5VVJ2
PDB IDs 2CU7 2DCE
GO Terms Enriched among Interactors ?
  • Signaling Adaptor Activity
  • Cyclic-di-GMP Binding
  • STING Complex
  • 2',3'-cyclic GMP-AMP Binding
  • Vacuole Organization
  • FHF Complex
  • Protein Localization To Adherens Junction
  • MPP7-DLG1-LIN7 Complex
  • Protein Localization To Perinuclear Region Of Cytoplasm
  • Manchette Assembly
  • Proton Channel Activity
  • Positive Regulation Of CGAS/STING Signaling Pathway

© Madhavi K. Ganapathiraju 2012-2026