HOXB13

Name	homeobox B13
Structure
Novel Interactors	1 novel interactors: RAB5C
Interactors	7 interactors: ALX4 ELK1 HOXD4 IRF4 MEIS1 POU2F1 ZNF490
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Morphogenesis Of An Epithelium Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Epidermis Development Response To Wounding Prostate Gland Development Response To Testosterone Regulation Of Growth Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development
GWAS	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 ) Prostate cancer ( 23104005 23535732 )
Entrez ID	10481
HPRD ID	05210
Ensembl ID	ENSG00000159184
Uniprot IDs	Q4KR72 Q92826
PDB IDs	2CRA 5EDN 5EEA 5EF6 5EG0 5EGO 5NO6 7PSX 8BYX
GO Terms Enriched among Interactors ?	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA Binding Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Pattern Specification Process Embryonic Skeletal System Morphogenesis Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Skeletal System Morphogenesis Positive Regulation Of Metabolic Process Hippocampal Neuron Apoptotic Process Animal Organ Morphogenesis Embryonic Organ Morphogenesis Regulation Of Macromolecule Metabolic Process Mediator Complex Binding Animal Organ Development Anterior/posterior Pattern Specification Cellular Response To Testosterone Stimulus Regulation Of Metabolic Process Cell Growth Involved In Cardiac Muscle Cell Development Plasma Membrane To Endosome Transport Cellular Developmental Process Transcription Regulator Activator Activity Nucleus Transcription Regulator Complex HMG Box Domain Binding Transcription Cis-regulatory Region Binding T-helper 17 Cell Lineage Commitment Regionalization Lens Morphogenesis In Camera-type Eye Positive Regulation Of Interleukin-13 Production