MYL9

Name	myosin light chain 9
Structure	No pdb structure
Novel Interactors	3 novel interactors: CEP250 PPP1R16B SLC12A5
Interactors	7 interactors: CDC42BPA HSPB1 LRRK2 MSGN1 MYH9 PRPF19 TXN2
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cytoskeleton Muscle Myosin Complex Cell Cortex Myosin Complex Myosin II Complex Myofibril Z Disc
	Molecular Function	Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding Metal Ion Binding
	Biological Process	Regulation Of Muscle Contraction Myofibril Assembly Stress Fiber Assembly Platelet Aggregation
Pathways	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
GWAS	No GWAS studies recorded
Entrez ID	10398
HPRD ID	17619
Ensembl ID	ENSG00000101335
Uniprot IDs	A0A384NY64 P24844
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Actomyosin Cytoskeleton Negative Regulation Of Protein Kinase C Signaling Platelet Aggregation Spindle Homotypic Cell-cell Adhesion Regulation Of Protein Processing Cell Leading Edge Cortical Granule Exocytosis Regulation Of Protein Maturation Cell Projection Thermosensory Behavior Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Regulation Of Anatomical Structure Morphogenesis Uropod Organization Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Regulation Of Cellular PH Regulation Of Intracellular PH Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Intracellular Protein Localization Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Kinase C Inhibitor Activity Identical Protein Binding Myosin II Filament Actomyosin Structure Organization Regulation Of Centriole-centriole Cohesion Regulation Of PH Positive Regulation Of Protein Autoubiquitination Response To Curcumin Actomyosin Contractile Ring Regulation Of Protein Kinase C Signaling Cortical Granule Cytoplasmic Actin-based Contraction Involved In Cell Motility Regulation Of Postsynapse Organization Cytoplasmic Side Of Mitochondrial Outer Membrane Positive Regulation Of Dopamine Receptor Signaling Pathway Multivesicular Body, Internal Vesicle Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Synaptic Vesicle Transport