Search Results for: ATIC

22 interactions involving ATIC - 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel CEBPA CCAAT enhancer binding protein alpha
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of granulopoiesis
  • Transcriptional regulation of granulopoiesis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Acute myeloid leukemia (AML)
Novel CIP2A cellular inhibitor of PP2A
Novel CPS1 carbamoyl-phosphate synthase 1
  • Urea cycle
  • Carglumic acid
  • Carbamoyl phosphate synthetase I deficiency
Novel DES desmin
  • Striated Muscle Contraction
  • Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
  • Dilated cardiomyopathy (DCM)
  • Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
  • Scapuloperoneal myopathy (SPM)
Novel LINC01554 long intergenic non-protein coding RNA 1554
Novel MAP3K7 mitogen-activated protein kinase kinase kinase 7
  • Activation of NF-kappaB in B cells
  • NOD1/2 Signaling Pathway
  • Downstream TCR signaling
  • FCERI mediated NF-kB activation
  • Ca2+ pathway
  • TAK1-dependent IKK and NF-kappa-B activation
  • activated TAK1 mediates p38 MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • TNFR1-induced NF-kappa-B signaling pathway
  • CLEC7A (Dectin-1) signaling
  • Ub-specific processing proteases
  • TICAM1,TRAF6-dependent induction of TAK1 complex
  • Interleukin-1 signaling
  • IRAK2 mediated activation of TAK1 complex
  • TRAF6-mediated induction of TAK1 complex within TLR4 complex
  • Alpha-protein kinase 1 signaling pathway
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Novel MTNR1A melatonin receptor 1A
  • Class A/1 (Rhodopsin-like receptors)
  • G alpha (i) signalling events
  • Ramelteon
  • Melatonin
  • Resveratrol
  • Agomelatine
  • Tasimelteon
Novel OGT O-linked N-acetylglucosamine (GlcNAc) transferase
  • HATs acetylate histones
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • UCH proteinases
  • Formation of WDR5-containing histone-modifying complexes
Novel RBM11 RNA binding motif protein 11
Novel SERPINB5 serpin family B member 5
  • S,S-(2-Hydroxyethyl)Thiocysteine
Novel VWC2L von Willebrand factor C domain containing 2 like
CEBPA CCAAT enhancer binding protein alpha
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of granulopoiesis
  • Transcriptional regulation of granulopoiesis
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Acute myeloid leukemia (AML)
CIP2A cellular inhibitor of PP2A
CPS1 carbamoyl-phosphate synthase 1
  • Urea cycle
  • Carglumic acid
  • Carbamoyl phosphate synthetase I deficiency
DES desmin
  • Striated Muscle Contraction
  • Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
  • Dilated cardiomyopathy (DCM)
  • Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
  • Scapuloperoneal myopathy (SPM)
LINC01554 long intergenic non-protein coding RNA 1554
MAP3K7 mitogen-activated protein kinase kinase kinase 7
  • Activation of NF-kappaB in B cells
  • NOD1/2 Signaling Pathway
  • Downstream TCR signaling
  • FCERI mediated NF-kB activation
  • Ca2+ pathway
  • TAK1-dependent IKK and NF-kappa-B activation
  • activated TAK1 mediates p38 MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • TNFR1-induced NF-kappa-B signaling pathway
  • CLEC7A (Dectin-1) signaling
  • Ub-specific processing proteases
  • TICAM1,TRAF6-dependent induction of TAK1 complex
  • Interleukin-1 signaling
  • IRAK2 mediated activation of TAK1 complex
  • TRAF6-mediated induction of TAK1 complex within TLR4 complex
  • Alpha-protein kinase 1 signaling pathway
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
MTNR1A melatonin receptor 1A
  • Class A/1 (Rhodopsin-like receptors)
  • G alpha (i) signalling events
  • Ramelteon
  • Melatonin
  • Resveratrol
  • Agomelatine
  • Tasimelteon
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
  • HATs acetylate histones
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • UCH proteinases
  • Formation of WDR5-containing histone-modifying complexes
RBM11 RNA binding motif protein 11

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