XYLB and STT3B

		XYLB	STT3B
Description		xylulokinase	STT3 oligosaccharyltransferase complex catalytic subunit B
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GO Annotations	Cellular Component	Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Protein-containing Complex Oligosaccharyltransferase Complex B
	Molecular Function	Nucleotide Binding D-xylulokinase Activity ATP Binding Kinase Activity Transferase Activity	Oligosaccharyl Transferase Activity Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Xylulose Metabolic Process Xylulose Catabolic Process Generation Of Precursor Metabolites And Energy D-glucuronate Catabolic Process To D-xylulose 5-phosphate D-xylose Metabolic Process Carbohydrate Phosphorylation	Protein Glycosylation Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine ERAD Pathway Post-translational Protein Modification
Pathways		Formation of xylulose-5-phosphate	Asparagine N-linked glycosylation Maturation of spike protein Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition PD-L1(CD274) glycosylation and translocation to plasma membrane
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Estimated glomerular filtration rate ( 30604766 31015462) Hippocampal volume ( 29860282) Major depressive disorder ( 29317602) P wave duration ( 24850809) Urinary metabolites ( 26352407)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Diabetic retinopathy in type 2 diabetes ( 33607655) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)
Interacting Genes			2 interacting genes: FILNC1 INCA1
Entrez ID		9942	201595
HPRD ID		06812	12268
Ensembl ID		ENSG00000093217	ENSG00000163527
Uniprot IDs		C9J0N9 O75191	Q8TCJ2
PDB IDs		4BC2 4BC3 4BC4 4BC5	6S7T
Enriched GO Terms of Interacting Partners?		PAM Complex, Tim23 Associated Import Motor Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Oligosaccharyl Transferase Activity Oligosaccharyltransferase Complex B TIM23 Mitochondrial Import Inner Membrane Translocase Complex Adenyl-nucleotide Exchange Factor Activity Oligosaccharyltransferase Complex Protein Import Into Mitochondrial Matrix Protein N-linked Glycosylation Via Asparagine Glycoprotein Catabolic Process Protein Localization To Mitochondrion	Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Sterol 14-demethylase Activity Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Xylulose Catabolic Process D-xylulokinase Activity Aspartate Family Amino Acid Metabolic Process Glycine N-methyltransferase Activity Methionine-glyoxylate Transaminase Activity Glycine:2-oxoglutarate Aminotransferase Activity 2-aminoadipate Transaminase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Hepatic Stellate Cell Proliferation Protein Tyrosine Kinase Collagen Receptor Activity RNA Strand-exchange Activity Eukaryotic Translation Initiation Factor 4F Complex Assembly Xylulose Metabolic Process Sarcosine Metabolic Process S-adenosylhomocysteine Metabolic Process Kynurenine-glyoxylate Transaminase Activity GET Complex Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Phosphorylation Regulation Of Fibroblast Proliferation D-xylose Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine
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