PMPCB and VGF

		PMPCB	VGF
Description		peptidase, mitochondrial processing subunit beta	VGF nerve growth factor inducible
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Processing Peptidase Complex	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Transport Vesicle Cytoplasmic Vesicle
	Molecular Function	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	Hormone Activity Neuropeptide Hormone Activity Growth Factor Activity
	Biological Process	Proteolysis Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Ovarian Follicle Development Response To Dietary Excess Generation Of Precursor Metabolites And Energy Signal Transduction Response To Cold Sexual Reproduction Insulin Secretion Response To Insulin Carbohydrate Homeostasis Glucose Homeostasis Defense Response To Bacterium Regulation Of Synaptic Plasticity Response To CAMP
Pathways		Mitochondrial protein import Processing of SMDT1	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation NGF-stimulated transcription
Drugs
Diseases
GWAS		Diverticular disease ( 30177863) Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		5 interacting genes: FXN MARK3 NPSR1 PMPCA PTGER4
Entrez ID		9512	7425
HPRD ID		07539	03717
Ensembl ID		ENSG00000105819	ENSG00000128564
Uniprot IDs		A0A9L9PXG6 A0A9L9PXH0 A0A9L9PXI7 B3KM34 G3V0E4 O75439 Q96CP5	O15240
PDB IDs			7D13 7D16 8H0G 8H0U
Enriched GO Terms of Interacting Partners?			Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Processing Peptidase Complex Mitochondrial Protein Processing Mitochondrial Calcium Ion Transmembrane Transport Metalloendopeptidase Activity Metallopeptidase Activity Calcium Ion Transmembrane Transport Protein Processing
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