ZNF804A and FAM171B

		ZNF804A	FAM171B
Description		zinc finger protein 804A	family with sequence similarity 171 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Axon Growth Cone Neuronal Cell Body Dendritic Spine Dendritic Shaft Presynapse Postsynapse Dendritic Microtubule	Membrane Synapse
	Molecular Function	Zinc Ion Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Gene Expression Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Positive Regulation Of Dendritic Spine Maintenance
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Alzheimer disease and age of onset ( 26830138) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 31043756) Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Broad depression or schizophrenia ( 30626913) Cervical artery dissection ( 25420145) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dentures ( 31235808) Feeling hurt ( 29500382) Loneliness (linear analysis) ( 27629369) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Obesity-related traits ( 23251661) Schizophrenia ( 30285260 29483656 28991256 25056061 18677311) Shoulder impingement or rotator cuff tear ( 33482370) Systolic blood pressure ( 30224653)	Blood protein levels ( 30072576) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 26631737) Urinary albumin-to-creatinine ratio ( 26631737) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		3 interacting genes: ATXN1 CRK SPP1	2 interacting genes: CAMK2D MPP3
Entrez ID		91752	165215
HPRD ID		12804	13907
Ensembl ID		ENSG00000170396	ENSG00000144369
Uniprot IDs		Q7Z570	Q6P995
PDB IDs
Enriched GO Terms of Interacting Partners?			Sodium Channel Inhibitor Activity Negative Regulation Of Sodium Ion Transport Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Titin Binding Regulation Of Relaxation Of Muscle Relaxation Of Cardiac Muscle Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Dendritic Microtubule Regulation Of Dendritic Spine Maintenance Positive Regulation Of Dendritic Spine Maintenance Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Relaxation Of Muscle Calcium/calmodulin-dependent Protein Kinase Activity Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of The Force Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy Actin-mediated Cell Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Heart Rate By Cardiac Conduction Sarcoplasmic Reticulum Membrane Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Dendritic Shaft Regulation Of Membrane Depolarization Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Conduction Long-term Synaptic Potentiation
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