KIFC2 and TEAD3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		KIFC2	TEAD3
Gene Name		kinesin family member C2	TEA domain family member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule	Nucleoplasm Transcription Factor Complex
	Molecular Function	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity	RNA Polymerase II Transcription Factor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Microtubule-based Movement Metabolic Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Gene Expression Hippo Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stem Cell Maintenance
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: GET4 MAPK8IP2 TAB1 TEAD3	13 interactors: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1
Entrez ID		90990	7005
HPRD ID		13916	04411
Ensembl ID		ENSG00000167702	ENSG00000007866
Uniprot IDs		Q96AC6	Q99594
PDB IDs
Enriched GO Terms of Interacting Partners?		JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade MAPK Cascade Nonassociative Learning Signal Transduction By Phosphorylation Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Stem Cell Maintenance Protein Insertion Into ER Membrane Activation Of MAPKKK Activity Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Signal Complex Assembly Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Protein Insertion Into Membrane Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of MAPK Cascade Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Stem Cell Maintenance Hippo Signaling Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Mating Behavior Behavioral Fear Response Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Fear Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Social Behavior Positive Regulation Of Phosphorylation Endoplasmic Reticulum Organization Positive Regulation Of Protein Modification Process Mating Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Stem Cell Differentiation Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Synaptic Transmission, Glutamatergic MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Transcription, DNA-templated Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Cell Proliferation Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Hippo Signaling Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Organ Morphogenesis Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Lens Fiber Cell Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Epithelial Cell Differentiation Notch Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
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