KIFC2 and TEAD3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		KIFC2	TEAD3
Description		kinesin family member C2	TEA domain transcription factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Dendrite Cytoplasm	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Microtubule-based Movement Axon Guidance Synaptic Vesicle Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Female Pregnancy Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Asymmetric Neuroblast Division
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)	Appendicular lean mass ( 33097823) Birth weight ( 31043758) Colorectal cancer or advanced adenoma ( 30510241) Offspring birth weight ( 31043758)
Interacting Genes		4 interacting genes: GET4 MAPK8IP2 TAB1 TEAD3	14 interacting genes: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 VGLL3 WWTR1 YAP1
Entrez ID		90990	7005
HPRD ID		13916	04411
Ensembl ID		ENSG00000167702	ENSG00000007866
Uniprot IDs		A0A2R8YEU8 Q96AC6	A0A7P0SNI2 Q99594
PDB IDs			5EMW 7CNL 7ZJQ 8P0M
Enriched GO Terms of Interacting Partners?			Transcription Coactivator Activity Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Fat Cell Proliferation Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Fat Cell Differentiation DNA-binding Transcription Activator Activity Positive Regulation Of Macromolecule Metabolic Process Hippo Signaling Heart Process Positive Regulation Of Metabolic Process DNA-binding Transcription Factor Binding Transcription Corepressor Activity Regulation Of Gene Expression Enterocyte Differentiation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Cell Population Proliferation Regulation Of The Force Of Skeletal Muscle Contraction Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Osteoblast Differentiation Mitochondrial Prohibitin Complex Nucleus Cis-regulatory Region Sequence-specific DNA Binding Apoptotic Signaling Pathway Negative Regulation Of Cell Population Proliferation TEAD-YAP Complex Regulation Of Cytochrome-c Oxidase Activity Amide Binding Endopeptidase Complex Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Signal Transduction By P53 Class Mediator Lens Fiber Cell Apoptotic Process Lateral Mesoderm Development
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