GGH and CLVS1

		GGH	CLVS1
Description		gamma-glutamyl hydrolase	clavesin 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Lysosome Vacuole Azurophil Granule Lumen Specific Granule Lumen Melanosome Extracellular Exosome Tertiary Granule Lumen	Endosome Golgi Apparatus Trans-Golgi Network Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Exopeptidase Activity Omega Peptidase Activity Hydrolase Activity Gamma-glutamyl-peptidase Activity	Protein Binding Lipid Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Tetrahydrofolylpolyglutamate Metabolic Process	Lysosome Organization
Pathways		Neutrophil degranulation	Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Adult body size ( 32376654) Bisphosphonate-associated atypical femoral fracture ( 31006051) Body mass index ( 25673413) Femur bone mineral density x serum urate levels interaction ( 34046847) Tyrosine levels ( 31560688) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: LIG4 SGTB	2 interacting genes: AHSP LRRK1
Entrez ID		8836	157807
HPRD ID		03299	14581
Ensembl ID		ENSG00000137563	ENSG00000177182
Uniprot IDs		A0A7I2V5X9 Q92820	Q8IUQ0
PDB IDs		1L9X
Enriched GO Terms of Interacting Partners?		Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency T Cell Differentiation Central Nervous System Development DNA Ligase Activity DN2 Thymocyte Differentiation TRC Complex Olfactory Nerve Development Right Ventricular Compact Myocardium Morphogenesis Right Ventricular Cardiac Muscle Tissue Morphogenesis Ear Morphogenesis Double-strand Break Repair Via Classical Nonhomologous End Joining Lymphoid Progenitor Cell Differentiation Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development DNA-dependent Protein Kinase-DNA Ligase 4 Complex Single Strand Break Repair Immunoglobulin V(D)J Recombination AMP Binding Lymphocyte Differentiation Chordate Embryonic Development Nonhomologous End Joining Complex Nucleotide-excision Repair, DNA Gap Filling In Utero Embryonic Development T Cell Activation Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Secondary Palate Development Regulation Of Growth Hormone Secretion Semicircular Canal Morphogenesis Ventricular Compact Myocardium Morphogenesis Adult Heart Development Olfactory Behavior Atrioventricular Canal Development Nose Development Phosphatidylinositol Bisphosphate Binding N6-methyladenosine-containing RNA Reader Activity Ventricular Trabecula Myocardium Morphogenesis Cellular Response To Lithium Ion Mononuclear Cell Differentiation Response To Lithium Ion Regulation Of Metal Ion Transport Female Genitalia Development Chemosensory Behavior Regulation Of Trophoblast Cell Migration	Gamma-glutamyl-peptidase Activity Tetrahydrofolylpolyglutamate Metabolic Process Hemopoiesis Omega Peptidase Activity Exopeptidase Activity Hemoglobin Binding Osteoclast Development Hemoglobin Complex Hemoglobin Metabolic Process Vacuole Folic Acid-containing Compound Metabolic Process Bone Resorption Pteridine-containing Compound Metabolic Process Cell Development Tertiary Granule Lumen
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