B3GALT4 and METTL18

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		B3GALT4	METTL18
Description		beta-1,3-galactosyltransferase 4	methyltransferase 18, RPL3 N3(tau)-histidine
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Nucleus Nucleolus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity Ganglioside Galactosyltransferase Activity	Protein Binding Methyltransferase Activity Transferase Activity Protein-L-histidine N-tele-methyltransferase Activity Heat Shock Protein Binding
	Biological Process	Ganglioside Biosynthetic Process Protein Glycosylation Protein O-linked Glycosylation Lipid Metabolic Process Glycosphingolipid Biosynthetic Process Oligosaccharide Biosynthetic Process Carbohydrate Derivative Biosynthetic Process	Cytoplasmic Translation Regulation Of Translation Regulation Of Translational Elongation Peptidyl-lysine Monomethylation Methylation Regulation Of Ribosome Biogenesis Regulation Of RRNA Processing
Pathways		Lewis blood group biosynthesis Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) LDL cholesterol ( 18193043)
Interacting Genes		5 interacting genes: DAAM1 DDX19B DYNLL1 METTL18 NOTCH1	4 interacting genes: B3GALT4 PHYHIP RGS2 YAE1
Entrez ID		8705	92342
HPRD ID		04370	14713
Ensembl ID		ENSG00000235863	ENSG00000171806
Uniprot IDs		B3KQP5 O96024 Q5STJ7	O95568
PDB IDs			4RFQ
Enriched GO Terms of Interacting Partners?		MAML1-RBP-Jkappa- ICN1 Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Vasculogenesis Involved In Coronary Vascular Morphogenesis Venous Endothelial Cell Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Distal Tubule Development Auditory Receptor Cell Fate Commitment Notch Signaling Involved In Heart Development Regulation Of Aorta Morphogenesis Growth Involved In Heart Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Epidermal Cell Fate Specification Endocardium Morphogenesis Coronary Sinus Valve Morphogenesis Retinal Cone Cell Differentiation Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Pro-B Cell Differentiation Cardiac Right Ventricle Formation Glomerular Mesangial Cell Development Enzyme Inhibitor Activity Cell Migration Involved In Endocardial Cushion Formation Chemical Synaptic Transmission, Postsynaptic Foregut Morphogenesis Compartment Pattern Specification Mitral Valve Formation Arterial Endothelial Cell Differentiation Cellular Response To Tumor Cell Regulation Of Cell Adhesion Involved In Heart Morphogenesis Cardiac Vascular Smooth Muscle Cell Development Negative Regulation Of Extracellular Matrix Constituent Secretion Positive Regulation Of Aorta Morphogenesis Coronary Vein Morphogenesis Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Cardiac Right Atrium Morphogenesis Deoxyribonuclease Inhibitor Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Protein-L-histidine N-tele-methyltransferase Activity Cell Surface Receptor Signaling Pathway Involved In Heart Development Negative Regulation Of Endothelial Cell Chemotaxis Mesangial Cell Development Luteolysis Endocardium Development Cardiac Atrium Morphogenesis T-helper 17 Type Immune Response Endocardial Cell Differentiation	Negative Regulation Of Glycine Import Across Plasma Membrane Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Ganglioside Galactosyltransferase Activity Adenylate Cyclase Inhibitor Activity Negative Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Striated Muscle Contraction Relaxation Of Cardiac Muscle Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Relaxation Of Smooth Muscle Relaxation Of Vascular Associated Smooth Muscle Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Smooth Muscle Contraction N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Ganglioside Biosynthetic Process Relaxation Of Muscle Negative Regulation Of Muscle Contraction Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Tissue Growth Hexosyltransferase Activity Ganglioside Metabolic Process Oligosaccharide Biosynthetic Process Brown Fat Cell Differentiation G-protein Alpha-subunit Binding Response To Amphetamine Glycosphingolipid Biosynthetic Process Maternal Process Involved In Female Pregnancy Negative Regulation Of Muscle Hypertrophy Negative Regulation Of JNK Cascade Negative Regulation Of Organ Growth Positive Regulation Of Heart Contraction Beta-tubulin Binding Negative Regulation Of Cardiac Muscle Hypertrophy Protein Tyrosine Kinase Binding Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Amine
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