MARCO and SCGB3A2

Number of citations of the paper that reports this interaction (PubMedID 12847263)
0

Data Source:
HPRD (in vivo)

		MARCO	SCGB3A2
Description		macrophage receptor with collagenous structure	secretoglobin family 3A member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Cytoplasm Plasma Membrane Membrane Endocytic Vesicle Membrane	Extracellular Region Extracellular Space Endocytic Vesicle Lumen
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Transmembrane Signaling Receptor Activity Cargo Receptor Activity Pattern Recognition Receptor Activity
	Biological Process	Immune System Process Endocytosis Receptor-mediated Endocytosis Phagocytosis, Engulfment Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Apoptotic Cell Clearance Innate Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Amyloid-beta Clearance
Pathways		Scavenging by Class A Receptors Scavenging by Class A Receptors	Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs		Titanium dioxide Silicon dioxide
Diseases
GWAS		Lung function (FVC) ( 30061609) Medication use (adrenergics, inhalants) ( 31015401) Triglyceride levels ( 32203549)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		3 interacting genes: SCGB3A1 SCGB3A2 SNCA	1 interacting genes: MARCO
Entrez ID		8685	117156
HPRD ID		05337	05940
Ensembl ID		ENSG00000019169	ENSG00000164265
Uniprot IDs		Q4ZG40 Q9UEW3	Q2L6B3 Q96PL1
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Neurotransmitter Secretion Regulation Of SNARE Complex Assembly Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Microtubule Polymerization SNARE Complex Assembly Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Platelet Alpha Granule Membrane Dynein Complex Binding Synaptic Vesicle Priming Extracellular Space Dopamine Transport Inclusion Body Positive Regulation Of Receptor Recycling Neurotransmitter Reuptake Catecholamine Biosynthetic Process Cellular Response To Epinephrine Stimulus Response To Magnesium Ion Behavioral Response To Cocaine Phospholipase Binding Regulation Of Neurotransmitter Uptake	Pattern Recognition Receptor Activity Amyloid-beta Clearance Cargo Receptor Activity Phagocytosis, Engulfment Apoptotic Cell Clearance Membrane Invagination Endocytic Vesicle Membrane Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Binding Collagen Trimer Phagocytosis G Protein-coupled Receptor Binding Receptor-mediated Endocytosis Positive Regulation Of ERK1 And ERK2 Cascade
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