STC2 and CPN1

		STC2	CPN1
Description		stanniocalcin 2	carboxypeptidase N subunit 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Response To Endoplasmic Reticulum Stress Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Calcium Ion Homeostasis Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	Proteolysis Peptide Metabolic Process Bradykinin Catabolic Process Protein Processing Protein Catabolic Process Response To Glucocorticoid
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Regulation of Complement cascade
Drugs			Zinc ORE-1001 Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		A body shape index ( 34021172) Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 23696881) Creatine kinase levels ( 29403010) Dermatomyositis ( 27153935) Femoral neck bone mineral density ( 22504420) General cognitive ability ( 29844566) Heel bone mineral density ( 30598549) Height ( 20881960) Liver enzyme levels ( 18940312) Liver enzyme levels (alanine transaminase) ( 22001757) Mean reticulocyte volume ( 32888494)
Interacting Genes		11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN	6 interacting genes: C3 C5 CDC42 CLEC4G CPN2 KNG1
Entrez ID		8614	1369
HPRD ID		04717	09120
Ensembl ID		ENSG00000113739	ENSG00000120054
Uniprot IDs		O76061 Q6FHC9	P15169
PDB IDs		7Y5Q 8A7D 8A7E 8HGH	2NSM
Enriched GO Terms of Interacting Partners?			Complement Activation, Lectin Pathway Complement Activation, GZMK Pathway Blood Microparticle Killing Of Cells Of Another Organism Complement Activation, Alternative Pathway Cell Killing Positive Regulation Of Vascular Endothelial Growth Factor Production Leukocyte Migration Complement Activation, Classical Pathway Humoral Immune Response Regulation Of Vascular Endothelial Growth Factor Production Chemokine Activity Endopeptidase Inhibitor Activity Endoplasmic Reticulum Lumen Complement Activation Immune System Process Signaling Receptor Binding C5L2 Anaphylatoxin Chemotactic Receptor Binding Extracellular Exosome Immune Effector Process Virus Coreceptor Activity Extracellular Region Immune Response Positive Regulation Of Activation Of Membrane Attack Complex GBD Domain Binding Storage Vacuole Hormone Activity Inflammatory Response Complement-dependent Cytotoxicity Classical-complement-pathway C3/C5 Convertase Complex Receptor Ligand Activity Vertebrate Eye-specific Patterning Endothelin Receptor Signaling Pathway Involved In Heart Process Glycosylated Region Protein Binding Leukocyte Chemotaxis Oviduct Epithelium Development Positive Regulation Of Type IIa Hypersensitivity Complement-mediated Synapse Pruning Extracellular Space Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Positive Regulation Of Endocytosis Negative Regulation Of Immature T Cell Proliferation In Thymus Immature T Cell Proliferation In Thymus Cell Chemotaxis Regulation Of Multicellular Organismal Process Positive Regulation Of Complement Activation Positive Regulation Of Hypersensitivity Tissue Development G Protein-coupled Receptor Signaling Pathway
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