LIPF and CLPS

Number of citations: 0 (PubMedID 11099794)
Data Source: HPRD (in vitro)

		LIPF	CLPS
Name		lipase F, gastric type	colipase
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Intracellular Membrane-bounded Organelle	Extracellular Region
	Molecular Function	Triacylglycerol Lipase Activity Protein Binding Lipid Binding Lipase Activity Malate Dehydrogenase Activity Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds Carboxylic Ester Hydrolase Activity	Enzyme Activator Activity Lipase Binding
	Biological Process	Malate Metabolic Process Lipid Metabolic Process Triglyceride Metabolic Process Lipid Catabolic Process	Retinoid Metabolic Process Lipid Metabolic Process Digestion Response To Bacterium Lipid Catabolic Process Response To Food
Pathways		Digestion of dietary lipid	Digestion of dietary lipid Retinoid metabolism and transport
Drugs		Orlistat Undecyl-Phosphinic Acid Butyl Ester	B-nonylglucoside (Hydroxyethyloxy)Tri(Ethyloxy)Octane METHOXYUNDECYLPHOSPHINIC ACID
GWAS		Estimated glomerular filtration rate in coronary artery disease and impaired kidney function ( 30809046 ) Intake of total sugars ( 31005972 )	Blood protein levels ( 30072576 )
Interacting Genes		3 interacting genes: CLPS MEOX2 PSEN2	4 interacting genes: GLP1R LIPF PNLIP PNLIPRP2
Entrez ID		8513	1208
HPRD ID		09063	00356
Ensembl ID		ENSG00000182333	ENSG00000137392
Uniprot IDs		P07098	A0A087WZW1 A0A087X0Q7 P04118
PDB IDs		1HLG	Not available
GO Terms Enriched among Interactors		Lipase Binding Activation Of Protein Kinase B Activity Ventricular Cardiac Muscle Cell Differentiation ErbB-3 Class Receptor Binding Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Regulation Of Organ Growth Positive Regulation Of Protein Autophosphorylation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB2-ERBB4 Signaling Pathway Endocardial Cell Differentiation ERBB4 Signaling Pathway Nickel Cation Binding ERBB4-ERBB4 Signaling Pathway Somite Specification Notch Receptor Processing Mitochondrion-endoplasmic Reticulum Membrane Tethering Gamma-secretase Complex Regulation Of Calcium Import Into The Mitochondrion Aspartic Endopeptidase Activity, Intramembrane Cleaving Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Negative Regulation Of Cell Size Rhythmic Synaptic Transmission Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Presynaptic Membrane Assembly Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Regulation Of Developmental Growth Apical Plasma Membrane Ventricular Trabecula Myocardium Morphogenesis Cardiac Muscle Cell Myoblast Differentiation Protein Tyrosine Kinase Activator Activity Cardioblast Differentiation Regulation Of Protein Autophosphorylation Segment Specification Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Cell Migration	Triacylglycerol Lipase Activity Lipase Activity Carboxylic Ester Hydrolase Activity Triglyceride Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Lipoprotein Lipase Activity Triglyceride Catabolic Process Phospholipase A1 Activity High-density Lipoprotein Particle Remodeling Acylglycerol Catabolic Process Lipid Catabolic Process Glycerolipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Sterol Homeostasis Cholesterol Homeostasis Glucagon-like Peptide 1 Receptor Activity Positive Regulation Of Triglyceride Lipase Activity Galactolipase Activity Fatty Acid Biosynthetic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Galactolipid Catabolic Process Lipid Homeostasis Glucagon Receptor Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Malate Dehydrogenase Activity Lipid Metabolic Process Lipid Digestion Response To Psychosocial Stress Carboxylic Acid Biosynthetic Process Retinyl-palmitate Esterase Activity Post-translational Protein Targeting To Membrane, Translocation Fatty Acid Metabolic Process Positive Regulation Of Lipase Activity Malate Metabolic Process Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Intestinal Cholesterol Absorption Cellular Response To Glucagon Stimulus Monoacylglycerol Lipase Activity Phosphatidylcholine Catabolic Process Activation Of Adenylate Cyclase Activity Intestinal Lipid Absorption Hydrolase Activity Small Molecule Biosynthetic Process Zymogen Granule Membrane Positive Regulation Of Adenylate Cyclase Activity Monocarboxylic Acid Metabolic Process