PYROXD2 and MYL4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PYROXD2	MYL4
Description		pyridine nucleotide-disulphide oxidoreductase domain 2	myosin light chain 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Cytosol Myosin Complex Myosin II Complex A Band
	Molecular Function	Protein Binding Oxidoreductase Activity	Actin Monomer Binding Calcium Ion Binding Myosin II Heavy Chain Binding Actin Filament Binding
	Biological Process	Mitochondrion Organization	Regulation Of The Force Of Heart Contraction Muscle Contraction Cardiac Muscle Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Metabolite levels ( 21931564 23281178) Obesity-related traits ( 23251661) Plasma pyridoxal phosphate to pyridoxal ratio ( 31641590) Serum metabolite levels ( 23093944 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407) Urinary metabolites (H-NMR features) ( 24586186)	Body mass index ( 26426971) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		3 interacting genes: APPBP2 CSNK2B MYL4	1 interacting genes: PYROXD2
Entrez ID		84795	4635
HPRD ID		12572	01176
Ensembl ID		ENSG00000119943	ENSG00000198336
Uniprot IDs		Q8N2H3	P12829
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Activin Receptor Signaling Pathway Protein Kinase CK2 Complex Negative Regulation Of Viral Life Cycle Symbiont-mediated Disruption Of Host Cell PML Body Release From Viral Latency Myosin II Heavy Chain Binding Adiponectin-activated Signaling Pathway Endothelial Tube Morphogenesis Protein Kinase Regulator Activity A Band PcG Protein Complex Peptidyl-threonine Phosphorylation Regulation Of Activin Receptor Signaling Pathway Actin Monomer Binding Myosin II Complex Regulation Of The Force Of Heart Contraction Cul2-RING Ubiquitin Ligase Complex	Descending Aorta Development Ascending Aorta Development Peptidyl-lysine Oxidation Platelet-derived Growth Factor Receptor-beta Signaling Pathway Protein-lysine 6-oxidase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor Protein Oxidation Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Bone Development Elastic Fiber Assembly Cellular Response To Chemokine Oxidoreductase Activity Muscle Cell Cellular Homeostasis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Small Molecule Binding
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