SLC37A3 and ZNF177

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		SLC37A3	ZNF177
Name		solute carrier family 37 member 3	zinc finger protein 177
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleus Blood Microparticle
	Molecular Function	Protein Binding Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Glucose 6-phosphate:phosphate Antiporter Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Xenobiotic Transmembrane Transport Glucose-6-phosphate Transport Phosphate Ion Transmembrane Transport Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		None recorded	2 novel interactors: KEAP1 TYK2
Interacting Genes		2 interacting genes: FOXJ1 ZNF177	20 interacting genes: ARHGAP21 BOLA2 BOLA2B CIB3 CSNK2A1 CT55 EXOC8 LMO1 MID2 MLH1 PMVK PRKAB2 PRKAR1B PSMB1 RHOU SLC37A3 SNAP25 SNAPC5 TRAF4 ZGPAT
Entrez ID		84255	7730
HPRD ID		15381	03175
Ensembl ID		ENSG00000157800	ENSG00000188629
Uniprot IDs		Q8NCC5	Q13360
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Central Tolerance Induction Positive Regulation Of Lung Ciliated Cell Differentiation Glomerular Parietal Epithelial Cell Development Positive Regulation Of B Cell Tolerance Induction Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Germinal Center Formation Metanephric Part Of Ureteric Bud Development Ciliary Basal Body Organization Regulation Of Germinal Center Formation Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Tolerance Induction Lung Epithelium Development Left/right Pattern Formation Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Tolerance Induction Regulation Of Tolerance Induction Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Regulation Of T Cell Differentiation In Thymus Establishment Or Maintenance Of Monopolar Cell Polarity Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of B Cell Activation DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Interleukin-6 Production Negative Regulation Of DNA-templated Transcription Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Humoral Immune Response Motile Cilium Assembly Axoneme Assembly Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of T Cell Differentiation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Lymphocyte Differentiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Epithelial Cell Differentiation Negative Regulation Of Adaptive Immune Response Negative Regulation Of T Cell Proliferation Negative Regulation Of Lymphocyte Proliferation Determination Of Bilateral Symmetry Negative Regulation Of Mononuclear Cell Proliferation Microtubule Organizing Center Organization Establishment Of Cell Polarity Determination Of Left/right Symmetry Microtubule Bundle Formation Negative Regulation Of Leukocyte Proliferation Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Hemopoiesis Blood Microparticle	Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly