KRTAP9-8 and NKD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP9-8	NKD1
Description		keratin associated protein 9-8	NKD inhibitor of Wnt signaling pathway 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Protein Phosphatase Type 2A Complex Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding PDZ Domain Binding Metal Ion Binding
	Biological Process		Eye Photoreceptor Cell Differentiation Axis Elongation Somatic Muscle Development Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Catabolic Process Convergent Extension Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Migration Involved In Somitogenic Axis Elongation Positive Regulation Of Non-canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		Keratinization
Drugs
Diseases
GWAS			Copper levels ( 26025379) Crohn's disease ( 22412388 28067908) Inflammatory bowel disease ( 28067908) Systolic blood pressure ( 30224653)
Interacting Genes		98 interacting genes: ADAM12 AQP1 BMP7 CATSPER1 CELF5 CNNM3 CRCT1 CREB5 CRY2 CYSRT1 DHRS1 DNAL4 FBXO34 GLRX3 GNE GUCD1 HOXA1 ITGB4 KLHL38 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP13-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MEOX2 NBPF19 NKD1 NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUBP2 NUFIP2 NUTF2 OLIG3 OTX1 P4HB PAX6 PHLDA1 POU4F2 PRKAB2 PRKAG1 RGS20 RNF8 SLC13A5 SLC15A3 SMCP TOX3 UNC119 VASN VGLL3 YIPF3 YY1 ZNF655	15 interacting genes: AKT1 CYSRT1 DVL3 KRTAP10-1 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-8 MDFI MORF4L1
Entrez ID		83901	85407
HPRD ID		19690	08482
Ensembl ID		ENSG00000187272	ENSG00000140807
Uniprot IDs		A0AAG2UVN4 Q9BYQ0	Q969G9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding Hair Cycle Identical Protein Binding Cytosol	Intermediate Filament Keratin Filament Cytosol
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