MFRP and C1QTNF5

Number of citations of the paper that reports this interaction (PubMedID 12944416)
0

Data Source:
HPRD (two hybrid)

		MFRP	C1QTNF5
Description		membrane frizzled-related protein	C1q and TNF related 5
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane	Extracellular Region Collagen Trimer Extracellular Space Plasma Membrane Bicellular Tight Junction Membrane Apical Plasma Membrane Lateral Plasma Membrane Transport Vesicle Protein-containing Complex Cell Projection
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Visual Perception Embryo Development Ending In Birth Or Egg Hatching Eye Photoreceptor Cell Development Retina Development In Camera-type Eye	Protein Secretion Inner Ear Development
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Intraocular pressure ( 30054594) Refractive error ( 32231278)	Blood protein levels ( 30072576) Lifespan ( 25918517)
Interacting Genes		2 interacting genes: C1QTNF5 PTN	5 interacting genes: GUCA1A MFRP SGTA SGTB SLC2A4
Entrez ID		83552	114902
HPRD ID		06941	10575
Ensembl ID		ENSG00000235718	ENSG00000223953
Uniprot IDs		Q9BY79	Q9BXJ0
PDB IDs			4F3J 4NN0
Enriched GO Terms of Interacting Partners?		Neuron Projection Arborization Decidualization Positive Regulation Of Axon Regeneration Negative Regulation Of Neural Precursor Cell Proliferation Dendrite Arborization Negative Regulation Of Long-term Synaptic Potentiation Neuron Projection Regeneration Regulation Of Hepatocyte Proliferation Protein-containing Complex Molecular Function Activator Activity Chondroitin Sulfate Binding Response To Auditory Stimulus Ovulation Cycle Negative Regulation Of Neuroblast Proliferation Dendrite Regeneration Leukocyte Chemotaxis Involved In Inflammatory Response Leukocyte Migration Involved In Inflammatory Response Regulation Of Axon Regeneration Positive Regulation Of Hepatocyte Proliferation Estrous Cycle Ossification Involved In Bone Remodeling Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Dendrite Development Regulation Of Neuron Projection Regeneration Regulation Of Neuroblast Proliferation Regulation Of Long-term Synaptic Potentiation Dendrite Development Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Regulation Of Myelination Positive Regulation Of Bone Mineralization Protein Phosphatase Inhibitor Activity Oogenesis Dendrite Morphogenesis Receptor Clustering Positive Regulation Of Biomineral Tissue Development Tissue Regeneration Positive Regulation Of Ossification Bone Mineralization Inner Ear Development Female Gamete Generation Positive Regulation Of Gliogenesis Extracellular Space Lateral Plasma Membrane Regulation Of Glial Cell Differentiation Regulation Of Stem Cell Population Maintenance Collagen Trimer Regulation Of Bone Mineralization	TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Positive Regulation Of Guanylate Cyclase Activity Protein Targeting To Membrane Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Guanylate Cyclase Regulator Activity Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Positive Regulation Of CGMP-mediated Signaling Calcium Sensitive Guanylate Cyclase Activator Activity Visual Perception Sensory Perception Of Light Stimulus Nervous System Process Cone Photoreceptor Outer Segment Establishment Of Protein Localization To Membrane Protein Targeting BAT3 Complex Binding Molecular Adaptor Activity Negative Regulation Of ERAD Pathway Insulin-responsive Compartment Glucose Import In Response To Insulin Stimulus White Fat Cell Proliferation Negative Regulation Of RIG-I Signaling Pathway Dehydroascorbic Acid Transport Fat Cell Proliferation D-glucose Transmembrane Transporter Activity Membrane Short-term Memory Negative Regulation Of Macrophage Cytokine Production Regulation Of CGMP-mediated Signaling Negative Regulation Of Interferon-beta Production Establishment Of Protein Localization To Organelle Tail-anchored Membrane Protein Insertion Into ER Membrane Trans-Golgi Network Transport Vesicle
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