FCRL4 and TFF2

Number of citations of the paper that reports this interaction (PubMedID 21982860)
0

Data Source:
BioGRID (pull down)

		FCRL4	TFF2
Description		Fc receptor like 4	trefoil factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Extracellular Region Extracellular Space
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	Protein Binding CXCR4 Chemokine Receptor Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Cell Surface Receptor Signaling Pathway	Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Gastric Acid Secretion Chemokine-mediated Signaling Pathway
Pathways
Drugs			Pidolic acid
Diseases
GWAS
Interacting Genes		8 interacting genes: BMP10 DERL1 DTX2 JAGN1 NINJ2 TFF1 TFF2 ZNF76	2 interacting genes: CFTR FCRL4
Entrez ID		83417	7032
HPRD ID		16168	01682
Ensembl ID		ENSG00000163518	ENSG00000160181
Uniprot IDs		Q96PJ5	Q03403
PDB IDs
Enriched GO Terms of Interacting Partners?		Maintenance Of Gastrointestinal Epithelium Epithelial Structure Maintenance	Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport TRAPPII Protein Complex Cellular Response To Forskolin Golgi-associated Vesicle Membrane TRAPP Complex Response To Forskolin Early Endosome To Golgi Transport Chloride Transmembrane Transporter Activity Sperm Capacitation Cell Surface Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Intra-Golgi Vesicle-mediated Transport Vesicle Coating Vesicle Tethering Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking
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